arsenic
Small moleculeexperimental
Arsenic is a chemical element; it has symbol As and atomic number 33. It is a metalloid and one of the pnictogens, and therefore shares many properties with its group 15 neighbors phosphorus and antimony. Arsenic is notoriously toxic. It occurs naturally in many minerals, usually in combination with sulfur and metals, but also as a pure elemental crystal. It has various allotropes, but only the grey form, which has a metallic appearance, is important to industry. — Wikipedia
Clinical trial activity
1 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Feb 1, 2008 (NCT01019083)
Timeline
2000s
- Jan 1, 2008
Earliest Phase 1 Sponsor(trial)
Indications
Mechanism of action
- Pyruvate dehydrogenase kinaseINHIBITOR
Pyruvate dehydrogenase kinase inhibitor
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (PDK2) ↗
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (PDK3) ↗
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (PDK4) ↗
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (PDK1) ↗
Chemistry & pharmacology
Loading structure…
SMILES
[As]- Mol. weight
- 74.9216 g/mol
- Chirality
- Achiral Molecule
- Inorganic
- Yes
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaArsenic ↗
- NCATSN712M78A8G ↗
- ChEMBLCHEMBL1231052 ↗
Also known as
- arsenic
- arsenic
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01019083 | Phase 1/Phase 2 (Phase 2) | Feb 1, 2008 | International Center for Diarrheal Disease Research, University of Gothenburg |
Showing 1 of 1 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| International Center for Diarrheal Disease Research | Academic/Hospital | 1 | 1 | 1 | 2008 |
| University of Gothenburg | Academic/Hospital | 1 | 0 | 1 | 2008 |
2 organizations
Page 1 / 1