cea-loaded dendritic cells
Vaccineexperimental
Clinical trial activity
4 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
2
Phase 3
0
Phase 4
0
Earliest trial started Feb 1, 1997 (NCT00004604)
Timeline
1990s
- Jan 1, 1997
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
- Bile Duct Neoplasms · Phase 1
- Breast Neoplasms · Phase 1
- Colorectal Neoplasms · Phase 1/Phase 2
- Gallbladder Neoplasms · Phase 1
- Head and Neck Neoplasms · Phase 1
- Liver Neoplasms · Phase 1
- Lung Neoplasms · Phase 1
- Neoplasm Metastasis · Phase 1/Phase 2
- Neoplasms · Phase 1
- Ovarian Neoplasms · Phase 1
- Pancreatic Neoplasms · Phase 1
- Stomach Neoplasms · Phase 1
- Testicular Neoplasms · Phase 1
Mechanism of action
- Carcinoembryonic antigen-related cell adhesion molecule 5Immunity, active
CEACAM5 immunity, active
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- antigen-specific cytotoxic t lymphocytes induced by dendritic cells infected by recombinant adeno-associated virus with cea gene
- cea-loaded dendritic cells
- cea pulsed dendritic cells
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01637805 | Phase 1 | May 1, 2012 | Nanjing Medical University |
| NCT00154713 | Phase 1/Phase 2 (Phase 2) | Jul 1, 2005 | Government of Taiwan, National Taiwan University |
| NCT00228189 | Phase 1/Phase 2 (Phase 2) | Dec 1, 2003 | Radboud University |
| NCT00004604 | Phase 1 | Feb 1, 1997 | Duke University, National Cancer Institute (NCI) |
Showing 4 of 4 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Duke University | Academic/Hospital | 1 | 1 | 1 | 1997 |
| Government of Taiwan | Government | 1 | 0 | 1 | 2005 |
| Nanjing Medical University | Academic/Hospital | 1 | 1 | 1 | 2012 |
| National Cancer Institute (NCI) | Government | 1 | 0 | 1 | 1997 |
| National Taiwan University | Academic/Hospital | 1 | 1 | 1 | 2005 |
| Radboud University | Academic/Hospital | 1 | 1 | 1 | 2003 |
6 organizations
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