cd22 car-t cells
Cell therapyexperimental
Clinical trial activity
39 trials · 34 clinical orgs · 0 marketing orgs
Phase 1
36
Phase 2
15
Phase 3
0
Phase 4
0
Earliest trial started Nov 20, 2014 (NCT02315612)
Timeline
Indications
Studied for
- Automobiles · Early Phase 1
- Burkitt Lymphoma · Phase 1
- Drugs, Investigational · Phase 1/Phase 2
- Hodgkin Disease · Phase 1
- Leukemia · Phase 1/Phase 2
- Leukemia, B-Cell · Phase 1/Phase 2
- Leukemia, Hairy Cell · Phase 1
- Leukemia, Lymphocytic, Chronic, B-Cell · Phase 1
- Leukemia, Lymphoid · Phase 1/Phase 2
- Lymphoma · Phase 1/Phase 2
- Lymphoma, B-Cell · Phase 1/Phase 2
- Lymphoma, B-Cell, Marginal Zone · Phase 1
- Lymphoma, Follicular · Phase 1
- Lymphoma, Large B-Cell, Diffuse · Phase 1
- Lymphoma, Large-Cell, Immunoblastic · Phase 1
- Lymphoma, Mantle-Cell · Phase 1
- Lymphoma, Non-Hodgkin · Phase 1
- Neoplasms · Phase 1/Phase 2
- Neoplasms, Plasma Cell · Phase 1
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma · Phase 2
- Precursor Cell Lymphoblastic Leukemia-Lymphoma · Phase 2
- Recurrence · Phase 1/Phase 2
- Waldenstrom Macroglobulinemia · Phase 1
Mechanism of action
- CD22Immunity, passive
CD22 immunity, passive
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- anti-cd22 car nk cells
- cd22 car-t
- retroviral vector-transduced autologous t cells to express cd22-specific cars
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07135466 | Phase 1/Phase 2 (Phase 2) | Nov 1, 2025 | Tel Aviv University |
| NCT07108868 | Phase 1 | Jun 23, 2025 | University of Tuebingen |
| NCT06326008 | Phase 1 | Dec 15, 2024 | Government of China |
| NCT06445803 | Phase 1 | May 31, 2024 | Fudan University, Government of China |
| NCT06408194 | Phase 1 | May 13, 2024 | Stanford University |
| NCT06343090 | N/A | Apr 12, 2024 | Government of China |
| NCT06340737 | Phase 1 | Mar 29, 2024 | Stanford University, The Leukemia and Lymphoma Society |
| NCT05674175 | Phase 1/Phase 2 (Phase 2) | Jan 25, 2023 | University of Pennsylvania |
| NCT05651100 | Phase 1/Phase 2 (Phase 2) | Dec 10, 2022 | Kecellitics Biotech Company Ltd |
| NCT05651178 | Early Phase 1 (Phase 1) | Aug 12, 2022 | Hrain Biotechnology Co., Ltd., Nanchang University |
| NCT05223686 | Phase 1 | Feb 10, 2022 | Hrain Biotechnology Co., Ltd., Jiao Tong University |
| NCT04815356 | Phase 1 | Dec 7, 2021 | National Cancer Institute (NCI) |
| NCT04782193 | Phase 1/Phase 2 (Phase 2) | May 23, 2021 | Chongqing Medical University, Chongqing Precision Biotech Co., Ltd, People's Liberation Army of China |
| NCT04781634 | Phase 1/Phase 2 (Phase 2) | Mar 7, 2021 | Chongqing Medical University, Chongqing Precision Biotech Co., Ltd, People's Liberation Army of China |
| NCT04788472 | Phase 1/Phase 2 (Phase 2) | Mar 5, 2021 | Yake Biotechnology Ltd., Zhejiang University |
| NCT04740203 | Phase 1/Phase 2 (Phase 2) | Jan 31, 2021 | Yake Biotechnology Ltd., Zhejiang University |
| NCT04723901 | Phase 1/Phase 2 (Phase 2) | Oct 20, 2020 | Shenzhen University |
| NCT04546906 | N/A | Sep 1, 2020 | Hebei Senlang Biotechnology Inc., Ltd., Ludaopei Hospital |
| NCT04648475 | Phase 1/Phase 2 (Phase 2) | Aug 25, 2020 | Chongqing Medical University, Chongqing Precision Biotech Co., Ltd |
| NCT04340167 | Phase 2 | May 1, 2020 | Beijing Boren Hospital |
Showing 20 of 39 trials
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Organizations
Research & Development (34)
34 organizations
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