calcitonin gene related peptide
Peptideexperimental
Calcitonin gene-related peptide (CGRP) is a neuropeptide that belongs to the calcitonin family. Human CGRP consists of two isoforms, CGRP alpha and CGRP beta. α-CGRP is a 37-amino acid neuropeptide formed by alternative splicing of the calcitonin/CGRP gene located on chromosome 11. β-CGRP is less studied. In humans, β-CGRP differs from α-CGRP by three amino acids and is encoded in a separate, nearby gene. The CGRP family includes calcitonin (CT), adrenomedullin (AM), and amylin (AMY). — Wikipedia
Clinical trial activity
13 trials · 9 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
1
Phase 3
1
Phase 4
1
Earliest trial started Jul 1, 2006 (NCT00358839)
Timeline
2020s
- Jan 1, 2025
Earliest Phase 3 Sponsor(trial)
Indications
Approved for
Studied for
Mechanism of action
- Calcitonin receptorSupplementation
CALCR supplementation
Chemistry & pharmacology
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaCalcitonin gene-related peptide ↗
Also known as
- calcitonin gene related peptide
- calcitonin gene related peptide
- calcitonin gene-related peptide
- calcitonin gene-related peptide
- cgrp
- cgrp
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07040813 | Phase 3 | Jun 6, 2025 | Norwegian University of Science and Technology, Sorlandet Hospital HF, South-Eastern Norway Regional Health Authority, Sykehuset Innlandet HF, Telemark Hospital Trust, University of Oslo |
| NCT04592952 | Phase 4 | Oct 8, 2020 | University of Copenhagen |
| NCT04452929 | N/A | Jul 22, 2020 | Novartis, University of Copenhagen |
| NCT03791515 | N/A | Jul 26, 2018 | University of Copenhagen |
| NCT03598075 | N/A | Jul 1, 2018 | University of Copenhagen |
| NCT03542357 | N/A | Feb 15, 2018 | University of Copenhagen |
| NCT03143465 | N/A | Aug 1, 2016 | University of Copenhagen |
| NCT03481400 | N/A | Jul 31, 2016 | University of Copenhagen |
| NCT02466334 | N/A | Jun 1, 2015 | University of Copenhagen |
| NCT01924052 | N/A | Jun 1, 2013 | University of Copenhagen |
| NCT00687947 | N/A | May 1, 2008 | Fresenius, University of Copenhagen |
| NCT00363532 | N/A | Sep 1, 2006 | University of Copenhagen |
| NCT00358839 | N/A | Jul 1, 2006 | Fresenius, University of Copenhagen |
Showing 13 of 13 trials
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Organizations
Research & Development (9)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Copenhagen | Academic/Hospital | 12 | 12 | 2 | 2006 |
| Fresenius | For profit | 2 | 0 | 1 | 2006 |
| Norwegian University of Science and Technology | Academic/Hospital | 1 | 0 | 1 | 2025 |
| Novartis | For profit | 1 | 0 | 1 | 2020 |
| Sorlandet Hospital HF | Academic/Hospital | 1 | 0 | 1 | 2025 |
| South-Eastern Norway Regional Health Authority | Government | 1 | 0 | 1 | 2025 |
| Sykehuset Innlandet HF | Academic/Hospital | 1 | 0 | 1 | 2025 |
| Telemark Hospital Trust | Academic/Hospital | 1 | 0 | 1 | 2025 |
| University of Oslo | Academic/Hospital | 1 | 1 | 1 | 2025 |
9 organizations
Page 1 / 1