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arhalofenate

Small moleculeexperimental

Clinical trial activity

7 trials · 24 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
6
Phase 3
1
Phase 4
0

Earliest trial started May 1, 2006 (NCT00353587)

Timeline

2000s

  1. Jan 1, 2006

    Earliest Phase 2 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CC(=O)NCCOC(=O)[C@H](Oc1cccc(C(F)(F)F)c1)c1ccc(Cl)cc1
Mol. weight
415.8 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Prodrug

Sources

Also known as

  • arhalofenate
  • arhalofenate
  • arhalofenate
  • arhalofenate
  • arhalofenate
  • cb-102
  • cb-102
  • jnj-39659100
  • jnj-39659100
  • m-102
  • m-102
  • mbx-102
  • mbx-102
  • mbx-102
  • mbx-102

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02252835Phase 2Aug 1, 2014CymaBay Therapeutics, Inc.
NCT02063997Phase 2Mar 1, 2014CymaBay Therapeutics, Inc.
NCT01416402Phase 2Aug 1, 2011CymaBay Therapeutics, Inc.
NCT01399008Phase 2Jun 1, 2011CymaBay Therapeutics, Inc.
NCT01336686Phase 2May 1, 2011CymaBay Therapeutics, Inc.
NCT00814372Phase 2Dec 1, 2008All India Institute of Medical Sciences, American Institute of Research, Amrita Institute of Medical Sciences, Association of International Professionals, dba Nevada Alliance Against Diabetes, Bangalore Diabetes Centre, Bharti Research Institute of Diabetes & Endocrinology, BYL Nair Hospital, Christian Medical College, Vellore, India, CymaBay Therapeutics, Inc., Deenanath Mangeshkar Hospital & Research Centre, DGD Research, Diabetes Thyroid Hormone Research Institute Pvt. Ltd., Diacon Hospital, Bangalore, Dr. V. Seshiah Diabetes Care & Research Institute, Fortis Hospitals, India, Kamineni Hospitals Pvt, Ltd., Kasturba Medical College, Mediciti Hospital, Medwin Hospital, Hyderabad, AP, India, M.S. Ramaiah Medical College, Bangalore, India, P.D. Hinduja Hospital and Medical Research Centre, Mumbai, PMG Research, Providence Clinical Research, Rajiv Gandhi University of Health Sciences
NCT00353587Phase 2/Phase 3 (Phase 3)May 1, 2006CymaBay Therapeutics, Inc.
Showing 7 of 7 trials
Page 1 / 1

Organizations

Research & Development (24)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
CymaBay Therapeutics, Inc.For profit7722006
All India Institute of Medical SciencesAcademic/Hospital1012008
American Institute of ResearchAcademic/Hospital1012008
Amrita Institute of Medical SciencesAcademic/Hospital1012008
Association of International Professionals, dba Nevada Alliance Against DiabetesAcademic/Hospital1012008
Bangalore Diabetes CentreAcademic/Hospital1012008
Bharti Research Institute of Diabetes & EndocrinologyAcademic/Hospital1012008
BYL Nair HospitalAcademic/Hospital1012008
Christian Medical College, Vellore, IndiaAcademic/Hospital1012008
Deenanath Mangeshkar Hospital & Research CentreAcademic/Hospital1012008
DGD ResearchFor profit1012008
Diabetes Thyroid Hormone Research Institute Pvt. Ltd.Academic/Hospital1012008
Diacon Hospital, BangaloreAcademic/Hospital1012008
Dr. V. Seshiah Diabetes Care & Research InstituteAcademic/Hospital1012008
Fortis Hospitals, IndiaAcademic/Hospital1012008
Kamineni Hospitals Pvt, Ltd.Academic/Hospital1012008
Kasturba Medical CollegeAcademic/Hospital1012008
Mediciti HospitalAcademic/Hospital1012008
Medwin Hospital, Hyderabad, AP, IndiaAcademic/Hospital1012008
M.S. Ramaiah Medical College, Bangalore, IndiaAcademic/Hospital1012008
24 organizations
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