CDEK
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mesothelin car t cells

Cell therapyexperimental

Clinical trial activity

27 trials · 26 clinical orgs · 0 marketing orgs

Phase 1
24
Phase 2
5
Phase 3
0
Phase 4
0

Earliest trial started Mar 30, 2012 (NCT01583686)

Timeline

2010s

  1. Jan 1, 2012

    Earliest Phase 1 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Also known as

  • anti-meso-car vector transduced t cells
  • anti-mesothelin car
  • anti-mesothelin car nk cells
  • anti-mesothelin car t cells
  • autologous t cells transfected with chimeric anti-mesothelin immunoreceptor ss1
  • cart-meso
  • hu-cart meso cells
  • mesothelin-car-t cells
  • mesothelin-targeted t cells
  • tai-meso-cart

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07066995Phase 1/Phase 2 (Phase 2)Apr 29, 2025Essen Biotech
NCT07010523N/AOct 15, 2024UTC Therapeutics Inc., Zhejiang University
NCT05783089Phase 1Apr 30, 2023Chinese Academy of Medical Sciences, Tsinghua University, UTC Therapeutics Inc.
NCT05623488Phase 1Jan 31, 2023University of Pennsylvania
NCT05372692N/AApr 12, 2022Nanjing Blue Shield Biotech Co.,Ltd, Zhejiang University
NCT05057715Phase 1Dec 31, 2021University of Pennsylvania, VCN Biosciences, S.L.
NCT04981691Phase 1Oct 1, 2021Jiao Tong University, UTC Therapeutics Inc.
NCT05531708Phase 1Apr 2, 2021Ningxia Medical University, UTC Therapeutics Inc.
NCT03814447Early Phase 1 (Phase 1)Jun 30, 2019Hrain Biotechnology Co., Ltd., Jiao Tong University
NCT03916679Phase 1/Phase 2 (Phase 2)Apr 20, 2019Zhejiang University
NCT03799913Early Phase 1 (Phase 1)Apr 10, 2019Hrain Biotechnology Co., Ltd., Zhejiang University
NCT03747965Phase 1Nov 30, 2018People's Liberation Army of China
NCT03692637Early Phase 1 (Phase 1)Nov 30, 2018Allife Medical Science and Technology Co., Ltd.
NCT03608618Phase 1Aug 27, 2018CTI Clinical Trial and Consulting Services, MaxCyte, Inc.
NCT03638193N/AJul 11, 2018Nanjing Medical University, Shenzhen BinDeBio Ltd.
NCT03545815Phase 1Mar 1, 2018People's Liberation Army of China
NCT03323944Phase 1Sep 15, 2017University of Pennsylvania
NCT03182803Phase 1/Phase 2 (Phase 2)Jun 7, 2017Ningbo No. 5 Hospital, Shanghai Cell Therapy Research Institute
NCT03054298Phase 1Mar 1, 2017University of Pennsylvania
NCT02930993Phase 1Aug 1, 2016China Meitan General Hospital, Marino Biotechnology Co., Ltd.
Showing 20 of 27 trials
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Organizations

Research & Development (26)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
University of PennsylvaniaAcademic/Hospital6612013
UTC Therapeutics Inc.For profit4022021
Zhejiang UniversityAcademic/Hospital4432019
Jiao Tong UniversityAcademic/Hospital3212016
People's Liberation Army of ChinaGovernment3312015
Hrain Biotechnology Co., Ltd.For profit2012019
Shanghai GeneChem Co., Ltd.For profit2222016
Allife Medical Science and Technology Co., Ltd.For profit1112018
China Meitan General HospitalAcademic/Hospital1112016
Chinese Academy of Medical SciencesAcademic/Hospital1112023
Cornell UniversityAcademic/Hospital1112016
CTI Clinical Trial and Consulting ServicesFor profit1012018
Department of DefenseGovernment1012016
Essen BiotechFor profit1112025
Fudan UniversityAcademic/Hospital1012016
Marino Biotechnology Co., Ltd.For profit1012016
MaxCyte, Inc.For profit1112018
Nanjing Blue Shield Biotech Co.,LtdFor profit1012022
Nanjing Medical UniversityAcademic/Hospital1012018
National Cancer Institute (NCI)Government1112012
26 organizations
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