Poloxalene
Small moleculeexperimental
Clinical trial activity
9 trials · 10 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
3
Phase 3
2
Phase 4
0
Earliest trial started Nov 1, 1997 (NCT00004408)
Timeline
Indications
Mechanism of action
- Unspecified targetSurfactant
surfactant
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- Yes
Oral
No
Parenteral
No
Topical
No
Sources
- NCATSLQA7B6G8JG ↗
- ChEMBLCHEMBL2108540 ↗
- ChEMBLCHEMBL2108134 ↗
Also known as
- anx-188
- anx-188
- lutrol f
- lutrol f
- pluracare
- pluracare
- pluronic
- pluronic
- pluronic block copolymer p123
- pluronic f68
- pluronic f68
- pluronic p123
- pluronic p123
- pluronic p123
- poloxamer
- poloxamer
- poloxamer 188
- poloxamer 188
- poloxamer 188
- poloxamer-188
- poloxamer-188
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05529134 | Phase 1/Phase 2 (Phase 2) | Oct 1, 2022 | Phoenicis Therapeutics |
| NCT04204954 | Phase 2/Phase 3 (Phase 3) | May 6, 2019 | Hospital Virgen de la Luz |
| NCT04858113 | N/A | Oct 1, 2018 | University of Plymouth |
| NCT03558958 | Phase 2 | Jul 31, 2018 | Charley's Fund, Phrixus Pharmaceuticals, Inc., University of Cincinnati |
| NCT01893060 | N/A | Jul 1, 2013 | University of Virginia |
| NCT01790087 | Phase 1 | Feb 1, 2013 | Mast Therapeutics |
| NCT01886001 | N/A | Nov 1, 2012 | University of Virginia |
| NCT00328211 | N/A | Sep 1, 2005 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Cincinnati |
| NCT00004408 | Phase 3 | Nov 1, 1997 | CytRx, Mast Therapeutics |
Showing 9 of 9 trials
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Organizations
Research & Development (10)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Mast Therapeutics | For profit | 2 | 2 | 2 | 1997 |
| University of Cincinnati | Academic/Hospital | 2 | 1 | 2 | 2005 |
| University of Virginia | Academic/Hospital | 2 | 2 | 1 | 2012 |
| Charley's Fund | Academic/Hospital | 1 | 0 | 1 | 2018 |
| CytRx | For profit | 1 | 0 | 1 | 1997 |
| Hospital Virgen de la Luz | Academic/Hospital | 1 | 1 | 1 | 2019 |
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Government | 1 | 0 | 1 | 2005 |
| Phoenicis Therapeutics | For profit | 1 | 1 | 1 | 2022 |
| Phrixus Pharmaceuticals, Inc. | For profit | 1 | 1 | 1 | 2018 |
| University of Plymouth | Academic/Hospital | 1 | 1 | 1 | 2018 |
10 organizations
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