winfuran

Small moleculeexperimental

Clinical trial activity

7 trials · 6 clinical orgs · 0 marketing orgs

Phase 1
2
Phase 2
5
Phase 3
3
Phase 4
0

Earliest trial started Mar 1, 2008 (NCT00638495)

Timeline

2000s

  1. Jan 1, 2008

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2008

    Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2008

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CN(C(=O)/C=C/c1ccoc1)[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5
Mol. weight
476.57 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No
Delivery
Oral

Oral

Yes

Parenteral

No

Topical

No

Sources

Also known as

  • 17-cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-epoxy-6beta-(n-methyl-trans-3-(3-furyl)acrylamido)morphinan hydrochloride
  • nalfurafine
  • nalfurafine
  • nalfurafine
  • nalfurafine
  • nalfurafine
  • nalfurafine
  • nalfurafine hcl
  • nalfurafine hcl
  • nalfurafine hcl
  • nalfurafine hydrochloride
  • nalfurafine hydrochloride
  • nalfurafine hydrochloride
  • nalfurafine hydrochloride
  • remitch
  • trk 820
  • trk-820
  • trk-820
  • trk-820
  • trk-820
  • trk-820
  • trk-820
  • winfuran

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04728984Phase 3Sep 7, 2020Sunshine Lake Pharma Co., Ltd.
NCT03002233Phase 1Nov 1, 2016Toray Industries, Inc
NCT01660243Phase 2Sep 1, 2012Toray Industries, Inc
NCT00793156Phase 3Dec 1, 2009Acologix, Inc.
NCT01248650Phase 1Dec 1, 2008SK Chemicals, Sungkyunkwan University, Toray Industries, Inc
NCT01513161Phase 3Apr 1, 2008Seoul National University, SK Chemicals, Toray Industries, Inc
NCT00638495Phase 2Mar 1, 2008Toray Industries, Inc
Showing 7 of 7 trials
Page 1 / 1

Organizations

Research & Development (6)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Toray Industries, IncFor profit5332008
SK ChemicalsFor profit2222008
Acologix, Inc.For profit1112009
Seoul National UniversityAcademic/Hospital1012008
Sungkyunkwan UniversityAcademic/Hospital1012008
Sunshine Lake Pharma Co., Ltd.For profit1112020
6 organizations
Page 1 / 1