trichloroethanoic acid

Small moleculeexperimental

Trichloroacetic acid is an analogue of acetic acid in which the three hydrogen atoms of the methyl group have all been replaced by chlorine atoms. Salts and esters of trichloroacetic acid are called trichloroacetates. — Wikipedia

Clinical trial activity

8 trials · 7 clinical orgs · 0 marketing orgs

Phase 1
1
Phase 2
3
Phase 3
2
Phase 4
3

Earliest trial started Mar 1, 2006 (NCT00422539)

Timeline

2000s

  1. Jan 1, 2006

    Earliest Phase 2 Sponsor(trial)

2010s

  1. Jan 1, 2011

    Earliest Phase 3 Sponsor(trial)

  2. Jan 1, 2016

    Earliest Phase 1 Sponsor(trial)

Indications

Approved for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

O=C(O)C(Cl)(Cl)Cl
Mol. weight
163.39 g/mol
Lipinski Ro5
Pass
Rule of 3
Yes
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • tcaa
  • tcaa
  • trichloracetic acid
  • trichloroacetic acid
  • trichloroacetic acid
  • trichloroacetic acid
  • trichloroacetic acid
  • trichloroacetic acid
  • trichloroacetic acid
  • trichloroacetic acid
  • trichloroethanoic acid
  • trichloroethanoic acid
  • trichloroethanoic acid
  • tricholoacetic acid

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04823520Phase 4Apr 1, 2021Assiut University
NCT04744103Phase 4Mar 10, 2021Government of Canada
NCT03153852Phase 4Dec 15, 2017Assiut University
NCT02892071Phase 1Sep 1, 2016University of Pittsburgh
NCT03071549Phase 3Apr 1, 2016Cairo University
NCT02905903N/AFeb 1, 2016Henry Ford Health System
NCT01586819Phase 3Sep 1, 2011Loyola University
NCT00422539Phase 2Mar 1, 2006Shahid Beheshti University of Medical Sciences
Showing 8 of 8 trials
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Organizations

Research & Development (7)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Assiut UniversityAcademic/Hospital2212017
Cairo UniversityAcademic/Hospital1112016
Government of CanadaGovernment1112021
Henry Ford Health SystemAcademic/Hospital1112016
Loyola UniversityAcademic/Hospital1112011
Shahid Beheshti University of Medical SciencesAcademic/Hospital1112006
University of PittsburghAcademic/Hospital1112016
7 organizations
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