Velsecorat
Small moleculeexperimental
Clinical trial activity
10 trials · 9 clinical orgs · 0 marketing orgs
Phase 1
8
Phase 2
2
Phase 3
0
Phase 4
0
Earliest trial started Sep 1, 2012 (NCT01636024)
Timeline
Indications
Mechanism of action
- Glucocorticoid receptorMODULATOR
NR3C1 modulator
Chemistry & pharmacology
Loading structure…
SMILES
C[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2c(cnn2-c2cccc(C(=O)N[C@@H]3CCOC3)c2)c1)c1ccc2c(c1)OCCO2- Mol. weight
- 606.63 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3666807 ↗
Also known as
- azd7594
- azd7594
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04072562 | Phase 1 | Sep 5, 2019 | AstraZeneca, Parexel |
| NCT03976869 | Phase 1 | Jul 22, 2019 | AstraZeneca, Parexel |
| NCT04002427 | Phase 1 | Jun 11, 2019 | AstraZeneca, Quotient |
| NCT03622112 | Phase 2 | Oct 12, 2018 | AstraZeneca, Parexel |
| NCT02928354 | Phase 1 | Nov 25, 2016 | AstraZeneca, Parexel |
| NCT02967159 | Phase 1 | Nov 24, 2016 | AstraZeneca, Parexel |
| NCT02648438 | Phase 1 | Jan 12, 2016 | AstraZeneca, Parexel |
| NCT02645253 | Phase 1 | Jan 1, 2016 | AstraZeneca, California Clinical Trials |
| NCT02479412 | Phase 2 | Jun 1, 2015 | AstraZeneca, Clinical Research Hamburg GmbH, Comac Medical, IKF Pneumologie GmbH, Frankfurt, Germany, Insaf GmbH, Wiesbaden, Germany, Parexel, University of Bonn |
| NCT01636024 | Phase 1 | Sep 1, 2012 | AstraZeneca |
Showing 10 of 10 trials
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Organizations
Research & Development (9)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| AstraZeneca | For profit | 10 | 10 | 2 | 2012 |
| Parexel | For profit | 7 | 0 | 2 | 2015 |
| California Clinical Trials | For profit | 1 | 0 | 1 | 2016 |
| Clinical Research Hamburg GmbH | For profit | 1 | 0 | 1 | 2015 |
| Comac Medical | For profit | 1 | 0 | 1 | 2015 |
| IKF Pneumologie GmbH, Frankfurt, Germany | Academic/Hospital | 1 | 0 | 1 | 2015 |
| Insaf GmbH, Wiesbaden, Germany | Academic/Hospital | 1 | 0 | 1 | 2015 |
| Quotient | For profit | 1 | 0 | 1 | 2019 |
| University of Bonn | Academic/Hospital | 1 | 0 | 1 | 2015 |
9 organizations
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