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ilaprazole

Trade name: noltec

Small moleculeexperimental

Ilaprazole is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. — Wikipedia

Clinical trial activity

35 trials · 22 clinical orgs · 0 marketing orgs

Phase 1
11
Phase 2
12
Phase 3
9
Phase 4
9

Earliest trial started Oct 1, 2004 (NCT00953381)

Timeline

2000s

  1. Jan 1, 2004

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2005

    Earliest Phase 1 Sponsor(trial)

  3. Jan 1, 2005

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

COc1ccnc(C[S+]([O-])c2nc3cc(-n4cccc4)ccc3[nH]2)c1C
Mol. weight
366.45 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Racemic Mixture
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • ilaprazole
  • ilaprazole
  • ilaprazole
  • ilaprazole
  • ilaprazole
  • ilaprazole
  • ilaprazole
  • iy81149
  • iy81149
  • iy 81149
  • iy 81149
  • iy-81149
  • iy-81149
  • iy-81149
  • iy-81149
  • noltec

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06284876Phase 3Aug 30, 2024Il-Yang Pharm. Co., Ltd.
NCT06725992Phase 1Jan 30, 2024Chonbuk National University, Il-Yang Pharm. Co., Ltd.
NCT05737082Phase 1Mar 10, 2023Hanmi Pharmaceutical, Jeonbuk National University
NCT05548543Phase 1Nov 19, 2022Hanmi Pharmaceutical, Jeonbuk National University
NCT05558150Phase 1Nov 11, 2022Il-Yang Pharm. Co., Ltd., Yonsei University
NCT05617651Phase 1Oct 27, 2022Il-Yang Pharm. Co., Ltd.
NCT05548387Phase 1Oct 1, 2022Hanmi Pharmaceutical, Jeonbuk National University
NCT05509543Phase 1Aug 24, 2022Il-Yang Pharm. Co., Ltd.
NCT05237297Phase 1Feb 17, 2022Il-Yang Pharm. Co., Ltd., Yonsei University
NCT05191875N/ADec 1, 2021Central South University
NCT05841394Phase 3Jul 16, 2021Livzon Pharmaceutical Group Inc.
NCT05410223N/AApr 6, 2021Central South University
NCT03444883Phase 3Aug 31, 2018Il-Yang Pharm. Co., Ltd.
NCT03342456Phase 4Dec 13, 2017Central South University, Livzon Pharmaceutical Group Inc., Yung Shin Pharm. Ind. Co., Ltd.
NCT03139253Phase 4May 30, 2017Shandong University
NCT02988089Phase 4Apr 20, 2017Binzhou Medical University, Liaocheng People's Hospital, People's Liberation Army of China, Shandong Provincial Hospital, Shandong University
NCT02998437Phase 1Dec 1, 2016Il-Yang Pharm. Co., Ltd., Yonsei University
NCT02648659Phase 4Mar 2, 2016Kyungpook University
NCT02638584Phase 4Dec 1, 2015Hallym University, Il-Yang Pharm. Co., Ltd.
NCT02401477Phase 4Dec 1, 2014Dongguk University, Il-Yang Pharm. Co., Ltd.
Showing 20 of 35 trials
Page 1 / 2

Organizations

Research & Development (22)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Il-Yang Pharm. Co., Ltd.For profit131332005
Livzon Pharmaceutical Group Inc.For profit111032004
Yonsei UniversityAcademic/Hospital4122014
Central South UniversityAcademic/Hospital3322017
Hanmi PharmaceuticalFor profit3312022
Jeonbuk National UniversityAcademic/Hospital3012022
Peking UniversityAcademic/Hospital3022004
Shandong UniversityAcademic/Hospital2212017
Binzhou Medical UniversityAcademic/Hospital1012017
Chonbuk National UniversityAcademic/Hospital1012024
Dongguk UniversityAcademic/Hospital1012014
Hallym UniversityAcademic/Hospital1012015
Inje UniversityAcademic/Hospital1112009
Kyungpook UniversityAcademic/Hospital1112016
Liaocheng People's HospitalAcademic/Hospital1012017
MDS PharmaFor profit1012005
People's Liberation Army of ChinaGovernment1012017
Shandong Provincial HospitalAcademic/Hospital1012017
Sun Yat-Sen UniversityAcademic/Hospital1012013
TakedaFor profit1112007
22 organizations
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