imarikiren
Small moleculeexperimental
Clinical trial activity
3 trials · 1 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Sep 1, 2014 (NCT02332824)
Timeline
Indications
Mechanism of action
- ReninINHIBITOR
REN inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
COCCCCn1c(C(=O)N(CC(C)C)[C@@H]2CNC[C@H](C(=O)N3CCOCC3)C2)nc2ccccc21- Mol. weight
- 499.66 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3990145 ↗
Also known as
- tak-272
- tak-272
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02367872 | Phase 1 | Feb 1, 2015 | Takeda |
| NCT02370615 | Phase 1 | Feb 1, 2015 | Takeda |
| NCT02332824 | Phase 2 | Sep 1, 2014 | Takeda |
Showing 3 of 3 trials
Page 1 / 1
Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Takeda | For profit | 3 | 3 | 2 | 2014 |
1 organizations
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