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silicone

Small moleculeexperimental

A silicone oil is any liquid polymerized siloxane with organic side chains. The most important member is polydimethylsiloxane. These polymers are of commercial interest because of their relatively high thermal stability and their lubricating properties. — Wikipedia

Clinical trial activity

18 trials · 23 clinical orgs · 0 marketing orgs

Phase 1
2
Phase 2
5
Phase 3
4
Phase 4
5

Earliest trial started Sep 1, 1985 (NCT00000140)

Timeline

1980s

  1. Jan 1, 1985

    Earliest Phase 3 Sponsor(trial)

2000s

  1. Jan 1, 2006

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2007

    Earliest Phase 1 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • dermacyn
  • mepilex
  • silicone
  • silicone
  • silicone oil
  • silicone oil
  • tg4040

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06129591Phase 1Jan 31, 2024University of Oklahoma
NCT03750422N/AJul 1, 2018Cosmetic Laser Dermatology, Goldman, Butterwick, Fitzpatrick and Groff
NCT03464760N/AMay 31, 2018Centre Hospitalier Universitaire de Nīmes, Phyco-Biotech, University of Nimes
NCT02318056N/ADec 1, 2015Southern Illinois University
NCT02518035Phase 4Jul 1, 2015Chang Gung University
NCT01861119Phase 3Apr 1, 2013Cha Medical University
NCT03139812Phase 4Jan 15, 2012University of California, Berkeley
NCT01439074Phase 4Sep 1, 2011Molnlycke Health Care AB
NCT01413789N/AJun 1, 2011Ghent University
NCT01055821Phase 2May 1, 2010Transgene
NCT00516958Phase 2May 1, 2007Sonoma Pharmaceuticals
NCT00449124Phase 1Mar 15, 2007National Institute of Allergy and Infectious Diseases (NIAID)
NCT00450775Phase 4Mar 1, 2007Dadeland Dermatology, Innovative Medical Research of South Florida, Inc
NCT00565552N/AJan 1, 2007Universitaetsklinikum Schleswig-Holstein
NCT00403702Phase 2/Phase 3 (Phase 3)Aug 1, 2006Asociación para Evitar la Ceguera en México
NCT00118495Phase 3Mar 1, 2006Kinsey Institute for Research in Sex, Gender and Reproduction, QualiLife Pharmaceuticals
NCT00754247Phase 4Mar 1, 2006University of Miami
NCT00000140Phase 3Sep 1, 1985National Eye Institute (NEI)
Showing 18 of 18 trials
Page 1 / 1

Organizations

Research & Development (23)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Asociación para Evitar la Ceguera en MéxicoAcademic/Hospital1112006
Centre Hospitalier Universitaire de NīmesAcademic/Hospital1112018
Cha Medical UniversityAcademic/Hospital1112013
Chang Gung UniversityAcademic/Hospital1112015
Cosmetic Laser DermatologyAcademic/Hospital1012018
Dadeland DermatologyAcademic/Hospital1012007
Ghent UniversityAcademic/Hospital1112011
Goldman, Butterwick, Fitzpatrick and GroffAcademic/Hospital1112018
Innovative Medical Research of South Florida, IncFor profit1112007
Kinsey Institute for Research in Sex, Gender and ReproductionAcademic/Hospital1012006
Molnlycke Health Care ABFor profit1112011
National Eye Institute (NEI)Government1111985
National Institute of Allergy and Infectious Diseases (NIAID)Government1112007
Phyco-BiotechFor profit1012018
QualiLife PharmaceuticalsFor profit1112006
Sonoma PharmaceuticalsFor profit1112007
Southern Illinois UniversityAcademic/Hospital1112015
TransgeneFor profit1112010
Universitaetsklinikum Schleswig-HolsteinAcademic/Hospital1112007
University of California, BerkeleyAcademic/Hospital1112012
23 organizations
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