phosphoric acid
Trade name: Freamine
Approved
Aug 24, 1971
Phosphoric acid is a colorless, odorless phosphorus-containing solid, and inorganic compound with the chemical formula H3PO4. It is commonly encountered as an 85% aqueous solution, which is a colourless, odourless, and non-volatile syrupy liquid. It is a major industrial chemical, being a component of many fertilizers. — Wikipedia
Clinical trial activity
2 trials · 2 clinical orgs · 4 marketing orgs
Earliest trial started Oct 1, 2012 (NCT02419157)
Timeline
1970s
- Aug 24, 1971
Earliest FDA Approval
- Sep 24, 1971
B. Braun — NDA Secondary Org
- May 14, 1976
ICU Medical Inc — NDA Secondary Org
Indications
Mechanism of action
- Amino acid transporterAGONIST
SLC1A5 agonist
Combination products
aminosyn m
with amino acids, potassium acetate, sodium chloride, magnesium
freamine iii w/ electrolytes
with potassium chloride, sodium acetate, amino acids, sodium chloride, magnesium
procalamine
with glycerin, calcium, potassium chloride, sodium acetate, amino acids, sodium chloride, magnesium
Approval history
- approvedAug 24, 1971
Chemistry & pharmacology
SMILES
O=P(O)(O)O- Mol. weight
- 97.99 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
- Delivery
- Parenteral
- Availability
- Discontinued
Oral
No
Parenteral
Yes
Topical
No
Sources
- WikipediaPhosphoric acid ↗
- ChEMBLCHEMBL1187 ↗
Also known as
- concise etchant
- condact
- e338
- e338
- k-etchant
- orthophosphoric acid
- phosphoric acid
- phosphoric acid
- phosphoric acid
- phosphoric acid
- phosphoric acid
- phosphoric acid
- phosphoric acid
- phosphoric acid
- phosphoric acid
- phosphoric acid
- uni-etch
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04207450 | N/A | Mar 15, 2019 | Universidade Federal do Para |
| NCT02419157 | N/A | Oct 1, 2012 | University of Guarulhos (UNG) |
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Universidade Federal do Para | Academic/Hospital | 1 | 1 | 1 | 2019 |
| University of Guarulhos (UNG) | Academic/Hospital | 1 | 1 | 1 | 2012 |
Marketing (4)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Abbott | For profit | NDA2 | — |
| B. Braun | For profit | NDA2 | Sep 24, 1971 |
| Braun Beteiligungs GmbH | For profit | NDA | — |
| ICU Medical Inc | For profit | NDA2 | May 14, 1976 |