sembragiline

Small moleculeexperimental

Clinical trial activity

7 trials · 5 clinical orgs · 0 marketing orgs

Phase 1
4
Phase 2
3
Phase 3
0
Phase 4
0

Earliest trial started Feb 1, 2008 (NCT00622752)

Timeline

2000s

  1. Jan 1, 2008

    Earliest Phase 2 Sponsor(trial)

2010s

  1. Jan 1, 2012

    Earliest Phase 1 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CC(=O)N[C@H]1CC(=O)N(c2ccc(OCc3cccc(F)c3)cc2)C1
Mol. weight
342.37 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • evt 302
  • evt 302
  • evt 302
  • rg1577
  • ro4602522
  • ro4602522
  • ro4602522
  • sembragiline

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02104648Phase 1Apr 1, 2014Roche
NCT01677754Phase 2Oct 24, 2012Roche
NCT01701089Phase 1Sep 1, 2012Roche
NCT01625806Phase 1Jul 1, 2012Roche
NCT01631422Phase 1Jun 1, 2012Roche
NCT00738595Phase 2Aug 1, 2008Evotec, Nuventra Pharma Sciences, Inc., Pharmaceutical Research Associates, Inc. (PRA)
NCT00622752Phase 2Feb 1, 2008Evotec, Parexel
Showing 7 of 7 trials
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Organizations

Research & Development (5)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
RocheFor profit5522012
EvotecFor profit2212008
Nuventra Pharma Sciences, Inc.For profit1012008
ParexelFor profit1012008
Pharmaceutical Research Associates, Inc. (PRA)For profit1012008
5 organizations
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