remd-477
mAbexperimental
Clinical trial activity
12 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
10
Phase 2
6
Phase 3
0
Phase 4
0
Earliest trial started Sep 1, 2015 (NCT02455011)
Timeline
Indications
Mechanism of action
- Glucagon receptorINHIBITOR
GCGR inhibitor
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4298213 ↗
Also known as
- remd-477
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07212868 | Phase 1 | Dec 1, 2025 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Texas, San Antonio |
| NCT06272695 | Phase 1 | Feb 15, 2024 | REMD Biotherapeutics, Inc. |
| NCT05696366 | Phase 1/Phase 2 (Phase 2) | Feb 28, 2023 | Juvenile Diabetes Research Foundation, University of California, San Diego |
| NCT05093517 | Early Phase 1 (Phase 1) | Nov 30, 2021 | University of Texas, San Antonio |
| NCT04779645 | Phase 2 | Jul 31, 2021 | REMD Biotherapeutics, Inc., University of California, San Diego |
| NCT04545411 | Phase 1/Phase 2 (Phase 2) | Sep 30, 2020 | REMD Biotherapeutics, Inc., University of California, San Diego |
| NCT04330625 | Phase 1 | Jul 1, 2020 | Duke University |
| NCT04253223 | Phase 1 | Feb 5, 2020 | Duke University |
| NCT03919617 | Phase 1/Phase 2 (Phase 2) | Apr 26, 2019 | REMD Biotherapeutics, Inc., University of California, San Diego |
| NCT03117998 | Phase 2 | Jun 30, 2017 | REMD Biotherapeutics, Inc. |
| NCT02715193 | Phase 1 | Mar 1, 2016 | REMD Biotherapeutics, Inc. |
| NCT02455011 | Phase 1/Phase 2 (Phase 2) | Sep 1, 2015 | REMD Biotherapeutics, Inc. |
Showing 12 of 12 trials
Page 1 / 1
Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| REMD Biotherapeutics, Inc. | For profit | 7 | 4 | 2 | 2015 |
| University of California, San Diego | Academic/Hospital | 4 | 4 | 1 | 2019 |
| Duke University | Academic/Hospital | 2 | 2 | 1 | 2020 |
| University of Texas, San Antonio | Academic/Hospital | 2 | 2 | 1 | 2021 |
| Juvenile Diabetes Research Foundation | Academic/Hospital | 1 | 0 | 1 | 2023 |
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Government | 1 | 0 | 1 | 2025 |
6 organizations
Page 1 / 1