stem cell factor
Recombinant proteinexperimental
Stem cell factor is a cytokine that binds to the c-KIT receptor (CD117). SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis, spermatogenesis, and melanogenesis. — Wikipedia
Clinical trial activity
4 trials · 5 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Dec 1, 1998 (NCT00003957)
Timeline
Indications
Mechanism of action
- Stem cell growth factor receptorINHIBITOR
KIT inhibitor
Chemistry & pharmacology
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaStem cell factor ↗
Also known as
- human stem cell factor
- stem cell factor
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00058045 | Phase 1 | Aug 1, 2002 | National Cancer Institute (NCI), State University of New York, Buffalo |
| NCT00006488 | Phase 1 | Nov 8, 2000 | National Center for Research Resources (NCRR) |
| NCT00005993 | Phase 1 | May 1, 1999 | National Cancer Institute (NCI), University of Minnesota |
| NCT00003957 | Phase 2 | Dec 1, 1998 | National Cancer Institute (NCI), Temple University |
Showing 4 of 4 trials
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Organizations
Research & Development (5)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Cancer Institute (NCI) | Government | 3 | 0 | 2 | 1998 |
| National Center for Research Resources (NCRR) | Government | 1 | 1 | 1 | 2000 |
| State University of New York, Buffalo | Academic/Hospital | 1 | 1 | 1 | 2002 |
| Temple University | Academic/Hospital | 1 | 1 | 1 | 1998 |
| University of Minnesota | Academic/Hospital | 1 | 1 | 1 | 1999 |
5 organizations
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