pyroxamide
Small moleculeexperimental
Clinical trial activity
1 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Apr 1, 2002 (NCT00042900)
Timeline
2000s
- Jan 1, 2002
Earliest Phase 1 Sponsor(trial)
Indications
Mechanism of action
- Histone deacetylaseINHIBITOR
HDAC1 inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
O=C(CCCCCCC(=O)Nc1cccnc1)NO- Mol. weight
- 265.31 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL353581 ↗
Also known as
- pyroxamide
- pyroxamide
- pyroxamide
- pyroxamide
- suberoyl-3-aminopyridineamide hydroxamic acid
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00042900 | Phase 1 | Apr 1, 2002 | Cornell University, National Cancer Institute (NCI) |
Showing 1 of 1 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Cornell University | Academic/Hospital | 1 | 1 | 1 | 2002 |
| National Cancer Institute (NCI) | Government | 1 | 0 | 1 | 2002 |
2 organizations
Page 1 / 1