pf-04236921
mAbexperimental
Clinical trial activity
8 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
5
Phase 3
0
Phase 4
0
Earliest trial started May 1, 2007 (NCT00626626)
Timeline
Indications
Studied for
- Arthritis, Rheumatoid · Phase 1
- Conjunctivitis, Allergic · Phase 1
- Crohn Disease · Phase 2
- Healthy Volunteers · Phase 1
- Hodgkin Disease · Phase 1/Phase 2
- Leukemia · Phase 1/Phase 2
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive · Phase 1/Phase 2
- Lupus Erythematosus, Systemic · Phase 2
- Lymphoma · Phase 1/Phase 2
- Lymphoma, Non-Hodgkin · Phase 1/Phase 2
- Multiple Myeloma · Phase 1/Phase 2
- Myelodysplastic Syndromes · Phase 1/Phase 2
- Rhinitis, Allergic · Phase 1
Mechanism of action
- Interleukin-6INHIBITOR
IL6 inhibitor
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2109613 ↗
Also known as
- pf-04236921
- pf-04236921
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03038971 | Phase 1 | Mar 30, 2017 | Greer Laboratories, ORA, Inc. |
| NCT02134262 | Phase 1/Phase 2 (Phase 2) | May 1, 2014 | Jichi Medical University, Takara Bio Inc. |
| NCT01405196 | Phase 2 | Dec 1, 2011 | Pfizer |
| NCT01345318 | Phase 2 | Jun 1, 2011 | Pfizer |
| NCT01287897 | Phase 2 | Feb 1, 2011 | Pfizer |
| NCT01166555 | Phase 1 | May 1, 2010 | Pfizer |
| NCT00838565 | Phase 1 | May 1, 2009 | Pfizer |
| NCT00626626 | Phase 1/Phase 2 (Phase 2) | May 1, 2007 | Pennsylvania State University |
Showing 8 of 8 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Pfizer | For profit | 5 | 5 | 2 | 2009 |
| Greer Laboratories | For profit | 1 | 1 | 1 | 2017 |
| Jichi Medical University | Academic/Hospital | 1 | 1 | 1 | 2014 |
| ORA, Inc. | For profit | 1 | 0 | 1 | 2017 |
| Pennsylvania State University | Academic/Hospital | 1 | 1 | 1 | 2007 |
| Takara Bio Inc. | For profit | 1 | 0 | 1 | 2014 |
6 organizations
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