pr1 peptide
Vaccineexperimental
Clinical trial activity
7 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
5
Phase 3
1
Phase 4
0
Earliest trial started Dec 1, 1999 (NCT00004918)
Timeline
Indications
Studied for
- Anemia, Refractory · Phase 1/Phase 2
- Healthy Volunteers · Phase 1
- Leukemia · Phase 3
- Leukemia, Lymphocytic, Chronic, B-Cell · Phase 1/Phase 2
- Leukemia, Myeloid, Acute · Phase 2
- Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative · Phase 2
- Leukemia, Myeloid, Chronic-Phase · Phase 1/Phase 2
- Myelodysplastic Syndromes · Phase 2
Mechanism of action
- Leukemia cellsImmunity, active
immunity, active - leukemia cells
Chemistry & pharmacology
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- NCATS54XUF2TZ7G ↗
- ChEMBLCHEMBL4297811 ↗
Also known as
- peptide vaccine (pr1 peptide)
- pr1 leukemia peptide vaccine
- wt1 and pr1 peptide
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02873767 | Phase 1 | Aug 1, 2016 | Hoosier Cancer Research Network |
| NCT00488592 | Phase 2 | Jun 1, 2007 | National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH) |
| NCT00513578 | Phase 2 | Jan 1, 2007 | The Vaccine Company |
| NCT00415857 | Phase 2 | Dec 1, 2006 | The Vaccine Company, University of Texas at Houston |
| NCT00270452 | Phase 1 | Dec 22, 2005 | National Heart, Lung, and Blood Institute (NHLBI) |
| NCT00454168 | Phase 3 | May 1, 2005 | The Vaccine Company |
| NCT00004918 | Phase 1/Phase 2 (Phase 2) | Dec 1, 1999 | National Cancer Institute (NCI), University of Texas at Houston |
Showing 7 of 7 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| The Vaccine Company | For profit | 3 | 2 | 2 | 2005 |
| National Heart, Lung, and Blood Institute (NHLBI) | Government | 2 | 2 | 2 | 2005 |
| University of Texas at Houston | Academic/Hospital | 2 | 1 | 1 | 1999 |
| Hoosier Cancer Research Network | Academic/Hospital | 1 | 1 | 1 | 2016 |
| National Cancer Institute (NCI) | Government | 1 | 1 | 1 | 1999 |
| National Institutes of Health (NIH) | Government | 1 | 0 | 1 | 2007 |
6 organizations
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