morab-004
mAbexperimental
Clinical trial activity
6 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
3
Phase 3
0
Phase 4
0
Earliest trial started Mar 1, 2009 (NCT00847054)
Timeline
Indications
Studied for
- Burkitt Lymphoma · Phase 1
- Colorectal Neoplasms · Phase 2
- Hodgkin Disease · Phase 1
- Intraocular Lymphoma · Phase 1
- Leukemia, Hairy Cell · Phase 1
- Leukemia, Large Granular Lymphocytic · Phase 1
- Leukemia, Lymphocytic, Chronic, B-Cell · Phase 1
- Leukemia-Lymphoma, Adult T-Cell · Phase 1
- Lymphoma · Phase 1
- Lymphoma, B-Cell, Marginal Zone · Phase 1
- Lymphoma, Follicular · Phase 1
- Lymphoma, Large B-Cell, Diffuse · Phase 1
- Lymphoma, Large-Cell, Anaplastic · Phase 1
- Lymphoma, Large-Cell, Immunoblastic · Phase 1
- Lymphoma, Mantle-Cell · Phase 1
- Lymphoma, Non-Hodgkin · Phase 1
- Lymphoma, T-Cell · Phase 1
- Lymphoma, T-Cell, Peripheral · Phase 1
- Lymphomatoid Granulomatosis · Phase 1
- Melanoma · Phase 2
- Neoplasm Metastasis · Phase 2
- Neoplasms · Phase 1
- Sezary Syndrome · Phase 1
- Testicular Neoplasms · Phase 1
- Transplantation · Phase 1
- Waldenstrom Macroglobulinemia · Phase 1
Mechanism of action
- Beta-lactamaseINHIBITOR
tem-1 inhibitor
Chemistry & pharmacology
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2109397 ↗
Also known as
- morab-004
- morab-004
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01748721 | Phase 1 | Nov 1, 2013 | Morphotek, National Cancer Institute (NCI) |
| NCT01773434 | Phase 1 | Dec 1, 2012 | Eisai |
| NCT01574716 | Phase 2 | May 1, 2012 | Icahn School of Medicine at Mount Sinai, Morphotek |
| NCT01507545 | Phase 2 | Mar 1, 2012 | Morphotek |
| NCT01335009 | Phase 2 | May 16, 2011 | Morphotek |
| NCT00847054 | Phase 1 | Mar 1, 2009 | Morphotek |
Showing 6 of 6 trials
Page 1 / 1
Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Morphotek | For profit | 5 | 5 | 2 | 2009 |
| Eisai | For profit | 1 | 1 | 1 | 2012 |
| Icahn School of Medicine at Mount Sinai | Academic/Hospital | 1 | 0 | 1 | 2012 |
| National Cancer Institute (NCI) | Government | 1 | 0 | 1 | 2013 |
4 organizations
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