ly-2452473

Small moleculeexperimental

Clinical trial activity

4 trials · 3 clinical orgs · 0 marketing orgs

Phase 1
2
Phase 2
2
Phase 3
0
Phase 4
0

Earliest trial started Oct 1, 2010 (NCT01160289)

Timeline

2010s

  1. Jan 1, 2010

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2011

    Earliest Phase 1 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CC(C)OC(=O)N[C@H]1Cc2c(n(Cc3ccccn3)c3ccc(C#N)cc23)C1
Mol. weight
374.44 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • ly2452473
  • ly2452473
  • ly2452473
  • ly-2452473
  • ly-2452473
  • ly-2452473

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02499497Phase 2Jul 1, 2015Harvard University, National Institute of Nursing Research (NINR)
NCT01401543Phase 1Jul 1, 2011Eli Lilly
NCT01275157Phase 1Jan 1, 2011Eli Lilly
NCT01160289Phase 2Oct 1, 2010Eli Lilly
Showing 4 of 4 trials
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Organizations

Research & Development (3)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Eli LillyFor profit3322010
Harvard UniversityAcademic/Hospital1112015
National Institute of Nursing Research (NINR)Government1012015
3 organizations
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