Lormetazepam

Small moleculeexperimental

Clinical trial activity

4 trials · 4 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
3
Phase 3
3
Phase 4
1

Earliest trial started Apr 1, 2008 (NCT00679900)

Timeline

2000s

  1. Jan 1, 2008

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CN1C(=O)C(O)N=C(c2ccccc2Cl)c2cc(Cl)ccc21
Mol. weight
335.19 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Racemic Mixture
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 7-chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2h-1,4-benzodiazepin-2-one
  • 7-chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2h-1,4-benzodiazepin-2-one
  • 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2h-1,4-benzodiazepin-2-one
  • 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2h-1,4-benzodiazepin-2-one
  • 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2h-1,4-benzodiazepin-2-one
  • chlorotemazepam
  • chlorotemazepam
  • lormetazepam
  • lormetazepam
  • lormetazepam
  • lormetazepam
  • lormetazepam
  • lormetazepam
  • lormetazepam
  • lormetazepam
  • (±)-lormetazepam
  • (±)-lormetazepam
  • methyllorazepam
  • methyllorazepam
  • methyllorazepam
  • methyllorazepam
  • methyllorazepam
  • n-methyllorazepam
  • n-methyllorazepam
  • n-methyllorazepam
  • (rs)-lormetazepam
  • (rs)-lormetazepam
  • wy-4082
  • wy-4082

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02374567Phase 3Jan 1, 2015Gottfried Wilhelm Leibniz Universität Hannover
NCT02022592Phase 4Jun 1, 2014Humboldt University, RWTH Aachen University
NCT00788515Phase 3Nov 1, 2008Sanofi
NCT00679900Phase 3Apr 1, 2008Sanofi
Showing 4 of 4 trials
Page 1 / 1

Organizations

Research & Development (4)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
SanofiFor profit2212008
Gottfried Wilhelm Leibniz Universität HannoverAcademic/Hospital1112015
Humboldt UniversityAcademic/Hospital1112014
RWTH Aachen UniversityAcademic/Hospital1012014
4 organizations
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