lcl-161

Small moleculeexperimental

Clinical trial activity

9 trials · 7 clinical orgs · 0 marketing orgs

Phase 1
6
Phase 2
4
Phase 3
0
Phase 4
0

Earliest trial started Nov 1, 2008 (NCT01098838)

Timeline

2000s

  1. Jan 1, 2008

    Earliest Phase 1 Sponsor(trial)

2010s

  1. Jan 1, 2012

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCCCC1
Mol. weight
500.64 g/mol
Lipinski Ro5
1 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • lcl-161
  • lcl-161
  • lcl-161

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02890069Phase 1Oct 14, 2016Novartis
NCT02649673Phase 1/Phase 2 (Phase 2)Mar 23, 2016Novartis, SCRI Development Innovations
NCT02098161Phase 2Dec 1, 2014Novartis, University of Texas at Houston
NCT01934634Phase 1Mar 1, 2014Delta Clinical Research, LLC, Novartis, US Oncology
NCT01955434Phase 2Nov 1, 2013Mayo Clinic, National Cancer Institute (NCI)
NCT01968915Phase 1Nov 1, 2013Novartis
NCT01617668Phase 2Aug 1, 2012Novartis
NCT01240655Phase 1Apr 1, 2011Novartis
NCT01098838Phase 1Nov 1, 2008Novartis
Showing 9 of 9 trials
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Organizations

Research & Development (7)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
NovartisFor profit8522008
Delta Clinical Research, LLCFor profit1012014
Mayo ClinicAcademic/Hospital1112013
National Cancer Institute (NCI)Government1012013
SCRI Development InnovationsFor profit1112016
University of Texas at HoustonAcademic/Hospital1112014
US OncologyFor profit1112014
7 organizations
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