Eganelisib
Small moleculeexperimental
Clinical trial activity
5 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
3
Phase 3
0
Phase 4
0
Earliest trial started Dec 1, 2015 (NCT02637531)
Timeline
Indications
Studied for
- Adrenocortical Carcinoma · Phase 1
- Breast Neoplasms · Phase 2
- Carcinoma · Phase 2
- Carcinoma, Non-Small-Cell Lung · Phase 1
- Carcinoma, Renal Cell · Phase 2
- Carcinoma, Squamous Cell · Phase 2
- Carcinoma, Transitional Cell · Phase 2
- Head and Neck Neoplasms · Phase 2
- Melanoma · Phase 1
- Mesothelioma · Phase 1
- Myeloid Cells · Phase 1
- Neoplasms · Phase 2
- Ovarian Neoplasms · Phase 1
- Squamous Cell Carcinoma of Head and Neck · Phase 2
- Urinary Bladder Neoplasms · Phase 2
Mechanism of action
Chemistry & pharmacology
Loading structure…
SMILES
C[C@H](NC(=O)c1c(N)nn2cccnc12)c1cc2cccc(C#Cc3cnn(C)c3)c2c(=O)n1-c1ccccc1- Mol. weight
- 528.58 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3984425 ↗
Also known as
- ipi-549
- ipi-549
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03795610 | Phase 2 | Jun 30, 2019 | University of California, San Diego, V Foundation |
| NCT03980041 | Phase 2 | Jun 30, 2019 | Bristol-Myers Squibb, Infinity Pharmaceuticals, Inc. |
| NCT03961698 | Phase 2 | Jun 1, 2019 | Infinity Pharmaceuticals, Inc., Roche |
| NCT03719326 | Phase 1 | Oct 15, 2018 | Arcus Biosciences, Inc., Infinity Pharmaceuticals, Inc. |
| NCT02637531 | Phase 1 | Dec 1, 2015 | Infinity Pharmaceuticals, Inc. |
Showing 5 of 5 trials
Page 1 / 1
Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Infinity Pharmaceuticals, Inc. | For profit | 4 | 3 | 2 | 2015 |
| Arcus Biosciences, Inc. | For profit | 1 | 1 | 1 | 2018 |
| Bristol-Myers Squibb | For profit | 1 | 0 | 1 | 2019 |
| Roche | For profit | 1 | 0 | 1 | 2019 |
| University of California, San Diego | Academic/Hospital | 1 | 1 | 1 | 2019 |
| V Foundation | Academic/Hospital | 1 | 0 | 1 | 2019 |
6 organizations
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