intestinal microbiota
Gut microbiota, gut microbiome, or gut flora are the microorganisms, including bacteria, archaea, fungi, and viruses, that live in the digestive tracts of animals. The gastrointestinal metagenome is the aggregate of all the genomes of the gut microbiota. The gut is the main location of the human microbiome. The gut microbiota has broad impacts, including effects on colonization, resistance to pathogens, maintaining the intestinal epithelium, metabolizing dietary and pharmaceutical compounds, controlling immune function, and even behavior through the gut–brain axis. — Wikipedia
Clinical trial activity
3 trials · 5 clinical orgs · 0 marketing orgs
Earliest trial started Oct 1, 2014 (NCT02857582)
Timeline
2010s
- Jan 1, 2014
Earliest Phase 2 Sponsor(trial)
Indications
Studied for
Mechanism of action
- microbiotaTissue restoration
microbiota tissue restoration
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaGut microbiota ↗
- WikipediaHuman gastrointestinal microbiota ↗
- WikipediaGut flora ↗
Also known as
- intestinal microbiota
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06931808 | Phase 4 | Mar 1, 2025 | Ningbo University |
| NCT02301000 | N/A | Nov 1, 2014 | Osaka University, University of Oslo |
| NCT02857582 | Phase 2 | Oct 1, 2014 | Karolinska Institute, Uppsala University |
Organizations
Research & Development (5)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Karolinska Institute | Academic/Hospital | 1 | 0 | 1 | 2014 |
| Ningbo University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Osaka University | Academic/Hospital | 1 | 1 | 1 | 2014 |
| University of Oslo | Academic/Hospital | 1 | 0 | 1 | 2014 |
| Uppsala University | Academic/Hospital | 1 | 1 | 1 | 2014 |