in111 anti-cd45 monoclonal antibody bc8
mAbexperimentalImaging agent
Clinical trial activity
2 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Jan 1, 2012 (NCT01300572)
Timeline
2010s
- Jan 1, 2012
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
- Anemia, Refractory · Phase 1
- Burkitt Lymphoma · Phase 1
- Hodgkin Disease · Phase 1
- Intraocular Lymphoma · Phase 1
- Leukemia, Hairy Cell · Phase 1
- Leukemia, Large Granular Lymphocytic · Phase 1
- Leukemia, Lymphocytic, Chronic, B-Cell · Phase 1
- Leukemia-Lymphoma, Adult T-Cell · Phase 1
- Leukemia, Myeloid, Acute · Phase 1
- Leukemia, Myelomonocytic, Chronic · Phase 1
- Lymphoma · Phase 1
- Lymphoma, B-Cell, Marginal Zone · Phase 1
- Lymphoma, Follicular · Phase 1
- Lymphoma, Large-Cell, Anaplastic · Phase 1
- Lymphoma, Large-Cell, Immunoblastic · Phase 1
- Lymphoma, Mantle-Cell · Phase 1
- Lymphoma, Non-Hodgkin · Phase 1
- Lymphoma, T-Cell · Phase 1
- Lymphoma, T-Cell, Peripheral · Phase 1
- Lymphomatoid Granulomatosis · Phase 1
- Myelodysplastic Syndromes · Phase 1
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma · Phase 1
- Sezary Syndrome · Phase 1
- Testicular Neoplasms · Phase 1
- Waldenstrom Macroglobulinemia · Phase 1
Mechanism of action
- Leukocyte common antigenINHIBITOR
PTPRC inhibitor
Chemistry & pharmacology
- Multi-specific
- No
- Imaging
- 111-Indium
Oral
No
Parenteral
No
Topical
No
Also known as
- in111 anti-cd45 monoclonal antibody bc8
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01678443 | Phase 1 | Dec 1, 2012 | National Cancer Institute (NCI), University of Washington |
| NCT01300572 | Phase 1 | Jan 1, 2012 | National Cancer Institute (NCI), University of Washington |
Showing 2 of 2 trials
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Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Cancer Institute (NCI) | Government | 2 | 0 | 1 | 2012 |
| University of Washington | Academic/Hospital | 2 | 2 | 1 | 2012 |
2 organizations
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