humax-il8
mAbexperimental
Clinical trial activity
8 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
6
Phase 3
0
Phase 4
0
Earliest trial started Aug 1, 2015 (NCT02536469)
Timeline
Indications
Studied for
- Antineoplastic Agents · Phase 1
- Antineoplastic Agents, Immunological · Phase 1
- Carcinoma, Hepatocellular · Phase 2
- Carcinoma, Non-Small-Cell Lung · Phase 2
- Carcinoma, Renal Cell · Phase 1
- COVID-19 · Phase 2
- Hematologic Neoplasms · Phase 2
- Immune Checkpoint Inhibitors · Phase 1
- Melanoma · Phase 1/Phase 2
- Molecular Mechanisms of Pharmacological Action · Phase 1
- Myelodysplastic Syndromes · Phase 1/Phase 2
- Neoplasms · Phase 2
- Neoplasms by Histologic Type · Phase 1
- Neoplasms by Site · Phase 1
- Nivolumab · Phase 1
- Prostatic Neoplasms · Phase 1/Phase 2
- Squamous Cell Carcinoma of Head and Neck · Phase 2
Mechanism of action
- Interleukin-8INHIBITOR
CXCL8 inhibitor
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2109617 ↗
Also known as
- humax-il8
- humax-il8
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05148234 | Phase 1/Phase 2 (Phase 2) | Dec 24, 2021 | National Cancer Institute (NCI) |
| NCT04848116 | Phase 2 | Apr 24, 2021 | Bristol-Myers Squibb, Johns Hopkins University |
| NCT04572451 | Phase 1 | Jan 31, 2021 | Bristol-Myers Squibb, University of Pittsburgh |
| NCT04347226 | Phase 2 | Apr 16, 2020 | Bristol-Myers Squibb, Columbia University |
| NCT04123379 | Phase 2 | Nov 30, 2019 | Bristol-Myers Squibb, Icahn School of Medicine at Mount Sinai |
| NCT03689699 | Phase 1/Phase 2 (Phase 2) | Oct 31, 2018 | Bristol-Myers Squibb, Columbia University |
| NCT03400332 | Phase 1/Phase 2 (Phase 2) | Jan 31, 2018 | Bristol-Myers Squibb |
| NCT02536469 | Phase 1 | Aug 1, 2015 | Bristol-Myers Squibb |
Showing 8 of 8 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Bristol-Myers Squibb | For profit | 7 | 2 | 2 | 2015 |
| Columbia University | Academic/Hospital | 2 | 2 | 1 | 2018 |
| Icahn School of Medicine at Mount Sinai | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Johns Hopkins University | Academic/Hospital | 1 | 1 | 1 | 2021 |
| National Cancer Institute (NCI) | Government | 1 | 1 | 1 | 2021 |
| University of Pittsburgh | Academic/Hospital | 1 | 1 | 1 | 2021 |
6 organizations
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