myeloid progenitor cells

Cell therapyexperimental

Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells. This process is called haematopoiesis. In vertebrates, the first definitive HSCs arise from the ventral endothelial wall of the embryonic aorta within the (midgestational) aorta-gonad-mesonephros region, through a process known as endothelial-to-hematopoietic transition. In adults, haematopoiesis occurs in the red bone marrow, in the core of most bones. The red bone marrow is derived from the layer of the embryo called the mesoderm. Recent study marks the first global discovery of hematopoietic stem cell (HSC) niches within invertebrate skeletons—overturning the long-held belief that skeletal hematopoiesis is unique to vertebrates, offering a novel evolutionary perspective on stem cell biology. — Wikipedia

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • myeloid progenitor cell
  • myeloid progenitor cells

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02129582Phase 1Jun 6, 2014Case Western Reserve University, National Cancer Institute (NCI)
NCT01297543Phase 1/Phase 2 (Phase 2)Mar 1, 2011Cellerant Therapeutics, Department of Health and Human Services
NCT00891137Phase 1Apr 1, 2009Cellerant Therapeutics, Department of Health and Human Services, University of Minnesota
Showing 3 of 3 trials
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Organizations

Research & Development (5)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Cellerant TherapeuticsFor profit2222009
Department of Health and Human ServicesGovernment2022009
Case Western Reserve UniversityAcademic/Hospital1112014
National Cancer Institute (NCI)Government1012014
University of MinnesotaAcademic/Hospital1012009
5 organizations
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