emd 273063
mAbexperimentalADC
Clinical trial activity
7 trials · 10 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
5
Phase 3
0
Phase 4
0
Earliest trial started Oct 1, 2001 (NCT00003750)
Timeline
Indications
Mechanism of action
- Disialoganglioside GD2CROSS-LINKING AGENT
Disialoganglioside GD2 cross-linking agent
- Disialoganglioside GD2Immunity, passive
Disialoganglioside GD2 immunity, passive
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
- Payload
- IL2
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2109422 ↗
Also known as
- emd 273063
- emd 273063 antibody, human
- hu14.18-il2
- hu14.18-il2
- hu14.18-il2
- hu14.18-interleukin-2 fusion protein
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03958383 | Phase 1/Phase 2 (Phase 2) | Jul 1, 2019 | Bristol-Myers Squibb, National Cancer Institute (NCI), Provenance Biopharmaceuticals, University of Wisconsin |
| NCT03209869 | Phase 1 | Mar 12, 2018 | Catherine Elizabeth Blair Memorial Foundation, Midwest Athletes Against Childhood Cancer, Inc., National Cancer Institute (NCI), Solving Kids’ Cancer, University of Wisconsin, Wade's Army |
| NCT01334515 | Phase 2 | Sep 1, 2011 | National Cancer Institute (NCI) |
| NCT00590824 | Phase 2 | Dec 1, 2007 | Merck Serono, National Cancer Institute (NCI), University of Wisconsin |
| NCT00082758 | Phase 2 | Aug 1, 2005 | Harvard University, National Cancer Institute (NCI), University of Wisconsin |
| NCT00109863 | Phase 2 | May 1, 2005 | National Cancer Institute (NCI), University of Wisconsin |
| NCT00003750 | Phase 1 | Oct 1, 2001 | National Cancer Institute (NCI), University of Wisconsin |
Showing 7 of 7 trials
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Organizations
Research & Development (10)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Cancer Institute (NCI) | Government | 7 | 3 | 2 | 2001 |
| University of Wisconsin | Academic/Hospital | 6 | 4 | 2 | 2001 |
| Bristol-Myers Squibb | For profit | 1 | 0 | 1 | 2019 |
| Catherine Elizabeth Blair Memorial Foundation | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Harvard University | Academic/Hospital | 1 | 0 | 1 | 2005 |
| Merck Serono | For profit | 1 | 0 | 1 | 2007 |
| Midwest Athletes Against Childhood Cancer, Inc. | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Provenance Biopharmaceuticals | For profit | 1 | 0 | 1 | 2019 |
| Solving Kids’ Cancer | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Wade's Army | Academic/Hospital | 1 | 0 | 1 | 2018 |
10 organizations
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