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Luminespib

Small moleculeexperimental

Clinical trial activity

24 trials · 21 clinical orgs · 0 marketing orgs

Phase 1
11
Phase 2
17
Phase 3
0
Phase 4
0

Earliest trial started Jul 1, 2007 (NCT00526045)

Timeline

2000s

  1. Jan 1, 2007

    Earliest Phase 1 Sponsor(trial)

2010s

  1. Jan 1, 2010

    Earliest Phase 2 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1
Mol. weight
465.55 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 5-(2,4-dihydroxy-5-isopropylphenyl)-4-(4-morpholin-4-ylmethylphenyl)isoxazole-3-carboxylic acid ethylamide
  • auy922
  • auy922
  • auy922
  • auy922
  • nvp-auy922
  • nvp-auy922
  • ver52296
  • ver 52296
  • ver-52296

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT01784640Phase 1Jan 1, 2014National Cancer Institute (NCI), University of California, Los Angeles
NCT01922583Phase 2Jan 1, 2014National Taiwan University
NCT01854034Phase 2Jul 1, 2013Harvard University
NCT01772797Phase 1Jun 1, 2013Novartis
NCT01752400Phase 2Jan 1, 2013Harvard University
NCT01613950Phase 1Dec 1, 2012Novartis
NCT01646125Phase 2Nov 1, 2012Novartis
NCT01485536Phase 2Aug 1, 2012Novartis, University of Texas at Houston
NCT01668173Phase 2Aug 1, 2012Cornell University, Novartis
NCT01484860Phase 2Jan 1, 2012Novartis, University of Toronto
NCT01404650Phase 2Dec 1, 2011Novartis, SCRI Development Innovations
NCT01402401Phase 2Nov 1, 2011Novartis
NCT01389583Phase 2Oct 1, 2011Chang Gung University, China Medical University, Government of Taiwan, Mackay Medical College, National Cheng Kung University, National Taiwan University, Taichung Veterans General Hospital, Taipei Veteran General hospital
NCT01602627Phase 1Sep 1, 2011Case Western Reserve University, National Cancer Institute (NCI), University of Rochester
NCT01361945Phase 1/Phase 2 (Phase 2)Jul 1, 2011Texas Tech University
NCT01259089Phase 1/Phase 2 (Phase 2)Mar 1, 2011Northwestern University
NCT01294826Phase 1Feb 1, 2011Novartis, University of Washington
NCT01226732Phase 1Nov 1, 2010Novartis, SCRI Development Innovations
NCT01124864Phase 2Oct 1, 2010Novartis
NCT01271920Phase 2Sep 1, 2010Novartis
Showing 20 of 24 trials
Page 1 / 2

Organizations

Research & Development (21)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
NovartisFor profit161022007
Harvard UniversityAcademic/Hospital2212013
National Cancer Institute (NCI)Government2012011
National Taiwan UniversityAcademic/Hospital2112011
SCRI Development InnovationsFor profit2222010
Case Western Reserve UniversityAcademic/Hospital1112011
Chang Gung UniversityAcademic/Hospital1012011
China Medical UniversityAcademic/Hospital1012011
Cornell UniversityAcademic/Hospital1112012
Government of TaiwanGovernment1112011
Mackay Medical CollegeAcademic/Hospital1012011
National Cheng Kung UniversityAcademic/Hospital1012011
Northwestern UniversityAcademic/Hospital1112011
Taichung Veterans General HospitalAcademic/Hospital1012011
Taipei Veteran General hospitalGovernment1012011
Texas Tech UniversityAcademic/Hospital1112011
University of California, Los AngelesAcademic/Hospital1112014
University of RochesterAcademic/Hospital1012011
University of Texas at HoustonAcademic/Hospital1112012
University of TorontoAcademic/Hospital1112012
21 organizations
Page 1 / 2