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pbr28

Small moleculeexperimentalImaging agent

Clinical trial activity

17 trials · 20 clinical orgs · 0 marketing orgs

Phase 1
11
Phase 2
5
Phase 3
0
Phase 4
2

Earliest trial started Jan 26, 2006 (NCT00283920)

Timeline

2000s

  1. Jan 1, 2006

    Earliest Phase 1 Sponsor(trial)

2010s

  1. Jan 1, 2015

    Earliest Phase 2 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

Chemistry & pharmacology

Imaging
11-carbon

Oral

No

Parenteral

No

Topical

No

Also known as

  • 11c pbr28
  • 11c pbr28
  • 11c-pbr28
  • 11c-pbr28
  • 11c-pbr28
  • (methyl-(11)c)n-acetyl-n-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine
  • pbr28
  • pbr28
  • prb28

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07131475Phase 2Oct 14, 2025Harvard University, National Institutes of Health (NIH), Navy SEAL Foundation, Uniformed Services University of the Health Sciences, University of South Florida
NCT05586581Phase 1/Phase 2 (Phase 2)Dec 31, 2022National Institute of Mental Health (NIMH), National Institutes of Health (NIH), Yale University
NCT04490096Phase 1Feb 25, 2021Biogen, University of Kansas, University of Miami, University of Pennsylvania
NCT04274998Early Phase 1 (Phase 1)Mar 1, 2020University of Pennsylvania
NCT04230174Phase 4Feb 29, 2020Genentech, Harvard University
NCT03705715Phase 1May 1, 2017University of Texas at Houston
NCT02831283Phase 2Jun 1, 2016Columbia University, National Institute on Aging (NIA)
NCT02702102Phase 2Dec 1, 2015Columbia University, National Institute on Aging (NIA)
NCT02233868Early Phase 1 (Phase 1)Sep 3, 2014National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT01881646Phase 4Jun 1, 2013Karolinska Institute, University of Copenhagen
NCT01547780Phase 1/Phase 2 (Phase 2)Jan 20, 2012National Institute of Mental Health (NIMH), Suburban Hospital, Uniformed Services University of the Health Sciences
NCT00547976Phase 1Oct 1, 2007National Institute of Mental Health (NIMH)
NCT00526916Phase 1Sep 4, 2007National Institute of Mental Health (NIMH)
NCT00459693N/AApr 9, 2007National Institute of Mental Health (NIMH)
NCT00432900Phase 1Feb 5, 2007National Institute of Neurological Disorders and Stroke (NINDS)
NCT00407693Phase 1Nov 28, 2006National Institute of Mental Health (NIMH)
NCT00283920Phase 1Jan 26, 2006National Institute of Mental Health (NIMH)
Showing 17 of 17 trials
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Organizations

Research & Development (20)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
National Institute of Mental Health (NIMH)Government7632006
Columbia UniversityAcademic/Hospital2212015
Harvard UniversityAcademic/Hospital2222020
National Institute on Aging (NIA)Government2012015
National Institutes of Health (NIH)Government2012022
Uniformed Services University of the Health SciencesGovernment2012012
University of PennsylvaniaAcademic/Hospital2212020
BiogenFor profit1012021
GenentechFor profit1012020
Karolinska InstituteAcademic/Hospital1112013
National Institute of Neurological Disorders and Stroke (NINDS)Government1112007
National Institute on Alcohol Abuse and Alcoholism (NIAAA)Government1112014
Navy SEAL FoundationAcademic/Hospital1012025
Suburban HospitalAcademic/Hospital1012012
University of CopenhagenAcademic/Hospital1012013
University of KansasAcademic/Hospital1012021
University of MiamiAcademic/Hospital1012021
University of South FloridaAcademic/Hospital1012025
University of Texas at HoustonAcademic/Hospital1112017
Yale UniversityAcademic/Hospital1112022
20 organizations
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