8-chloro-adenosine
Small moleculeexperimental
Clinical trial activity
3 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Jun 1, 2008 (NCT00714103)
Timeline
2000s
- Jan 1, 2008
Earliest Phase 1 Sponsor(trial)
Indications
Mechanism of action
- ATPINHIBITOR
ATP inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
Nc1ncnc2c1nc(Cl)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O- Mol. weight
- 301.69 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4594396 ↗
Also known as
- 8-chloro-adenosine
- 8-chloro-adenosine
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05263284 | Phase 1 | Jul 25, 2022 | City of Hope National Medical Center, National Cancer Institute (NCI) |
| NCT02509546 | Phase 1/Phase 2 (Phase 2) | Sep 2, 2015 | City of Hope National Medical Center, National Cancer Institute (NCI) |
| NCT00714103 | Phase 1 | Jun 1, 2008 | Food and Drug Administration, National Cancer Institute (NCI), University of Texas at Houston |
Showing 3 of 3 trials
Page 1 / 1
Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Cancer Institute (NCI) | Government | 3 | 0 | 2 | 2008 |
| City of Hope National Medical Center | Academic/Hospital | 2 | 2 | 2 | 2015 |
| Food and Drug Administration | Government | 1 | 0 | 1 | 2008 |
| University of Texas at Houston | Academic/Hospital | 1 | 1 | 1 | 2008 |
4 organizations
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