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Retagliptin

Small moleculeexperimental

Clinical trial activity

21 trials · 6 clinical orgs · 0 marketing orgs

Phase 1
15
Phase 2
6
Phase 3
4
Phase 4
0

Earliest trial started Jun 1, 2011 (NCT01969357)

Timeline

2010s

  1. Jan 1, 2011

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2012

    Earliest Phase 3 Sponsor(trial)

  3. Jan 1, 2013

    Earliest Phase 1 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

COC(=O)c1nc(C(F)(F)F)n2c1CN(C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F)CC2
Mol. weight
464.37 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • sp2086
  • sp2086

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06035406Phase 1Sep 30, 2023Hengrui Therapeutics, Inc.
NCT05692934Phase 1Jan 31, 2023Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT05415644Phase 1Jul 5, 2022Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT05054842Phase 3Oct 15, 2021Hengrui Therapeutics, Inc.
NCT04667143Phase 3Jan 31, 2021Hengrui Therapeutics, Inc.
NCT02826044Phase 1Jul 1, 2016Hengrui Therapeutics, Inc.
NCT02822534Phase 1Apr 1, 2016Hengrui Therapeutics, Inc.
NCT02817243Phase 1Mar 1, 2016Hengrui Therapeutics, Inc.
NCT02821871Phase 1Mar 1, 2016Hengrui Therapeutics, Inc.
NCT02817217Phase 1Mar 1, 2016Hengrui Therapeutics, Inc.
NCT02813863Phase 1Dec 1, 2015Hengrui Therapeutics, Inc.
NCT02815748Phase 1Aug 1, 2015Capital Medical University, Hengrui Therapeutics, Inc.
NCT02500485Phase 1May 1, 2015Hengrui Therapeutics, Inc.
NCT02815774Phase 1Jun 1, 2014Hengrui Therapeutics, Inc., Sichuan University
NCT02815787Phase 1Mar 1, 2014Hengrui Therapeutics, Inc., Shandong University
NCT02815722Phase 1Jul 1, 2013Hengrui Therapeutics, Inc., People's Liberation Army of China
NCT02815657Phase 1Apr 1, 2013Hengrui Therapeutics, Inc., People's Liberation Army of China
NCT01970046Phase 3Apr 1, 2013Hengrui Therapeutics, Inc., People's Liberation Army of China
NCT01970033Phase 3Dec 1, 2012Hengrui Therapeutics, Inc., People's Liberation Army of China
NCT01969318Phase 2Mar 1, 2012Hengrui Therapeutics, Inc., People's Liberation Army of China
Showing 20 of 21 trials
Page 1 / 2

Organizations

Research & Development (6)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Hengrui Therapeutics, Inc.For profit191932011
People's Liberation Army of ChinaGovernment6032011
Suzhou Suncadia Biopharmaceuticals Co., Ltd.For profit2212022
Capital Medical UniversityAcademic/Hospital1012015
Shandong UniversityAcademic/Hospital1012014
Sichuan UniversityAcademic/Hospital1012014
6 organizations
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