epitinib
Small moleculeexperimental
Clinical trial activity
2 trials · 1 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Oct 1, 2011 (NCT02590952)
Timeline
2010s
- Jan 1, 2011
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
Mechanism of action
EGFR inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
C#Cc1cccc(Nc2ncnc3cc(OC)c(NC(=O)N4CCN(CC)CC4)cc23)c1- Mol. weight
- 430.51 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL5314411 ↗
- ChEMBLCHEMBL3545121 ↗
Also known as
- epitinib
- epitinib
- hmpl-813
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03231501 | Phase 1 | Jan 26, 2018 | Hutchison MediPharma |
| NCT02590952 | Phase 1 | Oct 1, 2011 | Hutchison MediPharma |
Showing 2 of 2 trials
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Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Hutchison MediPharma | For profit | 2 | 2 | 1 | 2011 |
1 organizations
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