fenoterol
Small moleculeexperimental
Fenoterol is a β2-adrenergic receptor agonist and bronchodilator medication used in the treatment of asthma. — Wikipedia
Clinical trial activity
17 trials · 12 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
9
Phase 3
9
Phase 4
2
Earliest trial started Feb 1, 1990 (NCT02177370)
Timeline
Indications
Approved for
Mechanism of action
- Beta-2 adrenergic receptorAGONIST
ADRB2 agonist
Beta-2 adrenergic receptor stimulation in the lung causes relaxation of bronchial smooth muscle, bronchodilation, and increased bronchial airflow.
Chemistry & pharmacology
Loading structure…
SMILES
Cc1ccc2c(c1)Sc1ccc(C)cc1S2- Mol. weight
- 244.38 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaFenoterol ↗
- ChEMBLCHEMBL32800 ↗
- ChEMBLCHEMBL2106968 ↗
Also known as
- 1-(3,5-dihydroxyphenyl)-1-hydroxy-2-((4-hydroxyphenyl)isopropylamino)ethane
- 1-(3,5-dihydroxyphenyl)-1-hydroxy-2-((4-hydroxyphenyl)isopropylamino)ethane
- 1-(p-hydroxyphenyl)-2-((beta-hydroxy-beta-(3',5'-dihydroxyphenyl))ethyl)aminopropane
- 1-(p-hydroxyphenyl)-2-((beta-hydroxy-beta-(3',5'-dihydroxyphenyl))ethyl)aminopropane
- 3,5-dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)methyl)benzyl alcohol
- 3,5-dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)methyl)benzyl alcohol
- 5-{1-hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diol
- 5-{1-hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diol
- berodual
- berodual
- berodual
- berodual n
- berotec
- berotec
- berotec
- berotec 100
- berotec 200
- berotec [as hydrobromide]
- bronchodual
- duovent
- duovent
- duovent
- fenoterol
- fenoterol
- fenoterol
- fenoterol
- fenoterol
- fenoterol
- fenoterol
- fenoterol
- fenoterol
- fenoterol hcl
- fenoterol hydrobromide
- fenoterol hydrobromide
- fenoterol hydrobromide
- fenoterol hydrochloride
- fenoterol - ipratropium
- fenoterol, ipratropium drug combination
- fenoterolum
- fenoterolum
- iprafen
- phenoterol
- phenoterol
- phenoterol
- th-1165a [as hydrobromide salt]
- th-1165a [as hydrobromide salt]
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05294965 | Early Phase 1 (Phase 1) | Apr 27, 2022 | University of Basel |
| NCT05183841 | N/A | Mar 31, 2022 | University of Sao Paulo |
| NCT03910985 | Phase 4 | Apr 23, 2019 | CHU Mont-Godinne |
| NCT03031093 | N/A | Jun 1, 2017 | Federal University of Pernambuco, Universidade Federal do Rio Grande do Norte |
| NCT01933984 | N/A | Aug 1, 2013 | Changhua Christian Hospital |
| NCT02054299 | Phase 1 | Apr 1, 2013 | University of Goettingen |
| NCT01440335 | Phase 1 | Jul 10, 2011 | National Institute on Aging (NIA) |
| NCT01095016 | Phase 3 | Mar 1, 2010 | Chang Gung University, Otsuka |
| NCT00460577 | Phase 4 | Mar 1, 2007 | Novartis |
| NCT02176187 | Phase 3 | Apr 1, 2003 | Boehringer Ingelheim |
| NCT02176200 | Phase 3 | Apr 1, 2003 | Boehringer Ingelheim |
| NCT00274066 | Phase 3 | Oct 1, 2002 | Boehringer Ingelheim |
| NCT02173795 | Phase 3 | Oct 1, 2002 | Boehringer Ingelheim |
| NCT02182505 | Phase 3 | Sep 1, 1998 | Boehringer Ingelheim |
| NCT02182479 | Phase 3 | Apr 1, 1998 | Boehringer Ingelheim |
| NCT02173782 | Phase 3 | Feb 1, 1998 | Boehringer Ingelheim |
| NCT02177370 | Phase 3 | Feb 1, 1990 | Boehringer Ingelheim |
Showing 17 of 17 trials
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Organizations
Research & Development (12)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Boehringer Ingelheim | For profit | 8 | 8 | 1 | 1990 |
| Chang Gung University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Changhua Christian Hospital | Academic/Hospital | 1 | 1 | 1 | 2013 |
| CHU Mont-Godinne | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Federal University of Pernambuco | Academic/Hospital | 1 | 0 | 1 | 2017 |
| National Institute on Aging (NIA) | Government | 1 | 1 | 1 | 2011 |
| Novartis | For profit | 1 | 1 | 1 | 2007 |
| Otsuka | For profit | 1 | 1 | 1 | 2010 |
| Universidade Federal do Rio Grande do Norte | Academic/Hospital | 1 | 1 | 1 | 2017 |
| University of Basel | Academic/Hospital | 1 | 1 | 1 | 2022 |
| University of Goettingen | Academic/Hospital | 1 | 1 | 1 | 2013 |
| University of Sao Paulo | Academic/Hospital | 1 | 1 | 1 | 2022 |
12 organizations
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