hymecromone

Trade name: mendiaxon

Small moleculeexperimental

Clinical trial activity

6 trials · 7 clinical orgs · 0 marketing orgs

Phase 1
1
Phase 2
5
Phase 3
0
Phase 4
0

Earliest trial started Sep 1, 2005 (NCT00225537)

Timeline

2000s

  1. Jan 1, 2005

    Earliest Phase 2 Sponsor(trial)

2010s

  1. Jan 1, 2016

    Earliest Phase 1 Sponsor(trial)

Indications

Mechanism of action

  • Unspecified targetUnclear

    unclear

Chemistry & pharmacology

Loading structure…

SMILES

Cc1cc(=O)oc2cc(O)ccc12
Mol. weight
176.17 g/mol
Lipinski Ro5
Pass
Rule of 3
Yes
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 4-methylumbelliferone
  • 4-methylumbelliferone
  • bilcolic
  • bilicante
  • cantabilin
  • cantabiline
  • cantabiline
  • cholestil
  • cholspasmin
  • hymecromone
  • hymecromone
  • hymecromone
  • hymecromone
  • hymecromone
  • hymecromone
  • hymecromone
  • hymecromone
  • imecromone
  • lm-94
  • lm-94
  • mendiaxon

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06325696Phase 2Nov 17, 2024National Institute of Environmental Health Sciences (NIEHS)
NCT05295680Phase 2Nov 30, 2022Stanford University
NCT05386420N/AMay 23, 2022Fudan University
NCT05128929Phase 2Dec 1, 2021Stanford University
NCT02780752Phase 1/Phase 2 (Phase 2)Jul 1, 2016Stanford University
NCT00225537Phase 2Sep 1, 2005BioMonde Preparations Limited, MTmedical Institute of Health, University of Texas at Houston, University of Texas, San Antonio
Showing 6 of 6 trials
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Organizations

Research & Development (7)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Stanford UniversityAcademic/Hospital3312016
BioMonde Preparations LimitedFor profit1012005
Fudan UniversityAcademic/Hospital1112022
MTmedical Institute of HealthAcademic/Hospital1112005
National Institute of Environmental Health Sciences (NIEHS)Government1112024
University of Texas at HoustonAcademic/Hospital1012005
University of Texas, San AntonioAcademic/Hospital1012005
7 organizations
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