dnk333

Small moleculeexperimental

Clinical trial activity

4 trials · 1 clinical orgs · 0 marketing orgs

Phase 1
1
Phase 2
4
Phase 3
0
Phase 4
0

Earliest trial started Sep 1, 2003 (NCT01287325)

Timeline

2000s

  1. Jan 1, 2003

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2004

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@@H](/C=C/C(=O)N[C@@H]1CCCCNC1=O)Cc1ccc(Cl)c(Cl)c1
Mol. weight
624.41 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • dnk333
  • dnk333
  • dnk333
  • dnk333
  • dnk 333
  • dnk 333
  • dnk-333
  • dnk-333
  • dnk-333
  • n-((r,r)-(e)-1-(3,4-dichlorobenzyl)-3-(2-oxoazepan-3-yl)carbamoyl)allyl-n-methyl-3,5-bis(trifluoromethyl)benzamide

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT01033097Phase 2Nov 1, 2009Novartis
NCT00394173Phase 2Sep 1, 2006Novartis
NCT00699166Phase 2Apr 1, 2004Novartis
NCT01287325Phase 1/Phase 2 (Phase 2)Sep 1, 2003Novartis
Showing 4 of 4 trials
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Organizations

Research & Development (1)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
NovartisFor profit4412003
1 organizations
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