deferitazole
Small moleculeexperimental
Clinical trial activity
14 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
9
Phase 2
5
Phase 3
0
Phase 4
0
Earliest trial started Nov 1, 2009 (NCT01039636)
Timeline
Indications
Mechanism of action
- IronCHELATING AGENT
Iron chelating agent
Chemistry & pharmacology
Loading structure…
SMILES
COCCOCCOCCOc1cccc(C2=N[C@@](C)(C(=O)O)CS2)c1O- Mol. weight
- 399.47 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL487465 ↗
Also known as
- 3''-(ho)-desazadesferrithiocin-polyether
- 4,5-dihydro-2-(2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl)-4-methyl-4-thiazolecarboxylic acid
- deferitazole
- deferitazole
- deferitazole
- deferitazole
- fbs0701
- fbs0701
- fbs0701
- spd602
- ssp-004184
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01927913 | Phase 2 | Jul 1, 2014 | American University of Beirut, Shire |
| NCT02065401 | Phase 1 | Feb 1, 2014 | Shire |
| NCT01989169 | Phase 1 | Nov 1, 2013 | Clinical Pharmacology of Miami, Shire |
| NCT01979185 | Phase 1 | Nov 1, 2013 | Clinical Pharmacology of Miami, Shire |
| NCT01905540 | Phase 1 | Aug 1, 2013 | Clinical Pharmacology of Miami, Shire |
| NCT01905553 | Phase 1 | Aug 1, 2013 | Clinical Pharmacology of Miami, Shire |
| NCT01824446 | Phase 1 | Apr 1, 2013 | Shire |
| NCT01732263 | Phase 1 | Dec 1, 2012 | Clinical Pharmacology of Miami, Shire |
| NCT01716455 | Phase 1 | Nov 1, 2012 | Clinical Pharmacology of Miami, Shire |
| NCT01604941 | Phase 2 | Sep 1, 2012 | Shire, University of Milan |
| NCT01671111 | Phase 2 | Aug 1, 2012 | Harvard University, Shire |
| NCT01363908 | Phase 2 | Aug 1, 2011 | Harvard University, Shire |
| NCT01186419 | Phase 2 | Aug 1, 2010 | Harvard University, Shire |
| NCT01039636 | Phase 1 | Nov 1, 2009 | FerroKin BioSciences, Harvard University |
Showing 14 of 14 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Shire | For profit | 13 | 13 | 2 | 2010 |
| Clinical Pharmacology of Miami | For profit | 6 | 0 | 1 | 2012 |
| Harvard University | Academic/Hospital | 4 | 0 | 2 | 2009 |
| American University of Beirut | Academic/Hospital | 1 | 0 | 1 | 2014 |
| FerroKin BioSciences | For profit | 1 | 1 | 1 | 2009 |
| University of Milan | Academic/Hospital | 1 | 0 | 1 | 2012 |
6 organizations
Page 1 / 1