pf-04991532

Small moleculeexperimental

Clinical trial activity

11 trials · 2 clinical orgs · 0 marketing orgs

Phase 1
9
Phase 2
2
Phase 3
0
Phase 4
0

Earliest trial started Apr 1, 2010 (NCT01102673)

Timeline

2010s

  1. Jan 1, 2010

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2011

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

O=C(O)c1ccc(NC(=O)[C@H](CC2CCCC2)n2cnc(C(F)(F)F)c2)nc1
Mol. weight
396.37 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 6-(3-cyclopentyl-2-(4-trifluoromethyl)-1h-imidazol-1-yl)propanamido)nicotinic acid
  • pf-049
  • pf-0499132
  • pf-04991532
  • pf-04991532
  • pf-04991532
  • pf-04991532

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02117505Phase 1Apr 1, 2014Johnson and Johnson
NCT01469065Phase 1Dec 1, 2011Pfizer
NCT01469481Phase 1Nov 1, 2011Pfizer
NCT01369602Phase 1Jul 1, 2011Pfizer
NCT01370343Phase 1Jul 1, 2011Pfizer
NCT01369277Phase 1Jun 1, 2011Pfizer
NCT01336738Phase 2Jun 1, 2011Pfizer
NCT01338870Phase 2Jun 1, 2011Pfizer
NCT01351129Phase 1May 1, 2011Pfizer
NCT01129258Phase 1Jun 1, 2010Pfizer
NCT01102673Phase 1Apr 1, 2010Pfizer
Showing 11 of 11 trials
Page 1 / 1

Organizations

Research & Development (2)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
PfizerFor profit101022010
Johnson and JohnsonFor profit1112014
2 organizations
Page 1 / 1