omidenepag

Trade name: Omlonti

Small moleculeapproved

Approved

Sep 22, 2022

Clinical trial activity

13 trials · 1 clinical orgs · 1 marketing orgs

Phase 1
2
Phase 2
11
Phase 3
8
Phase 4
0

Earliest trial started Jul 1, 2012 (NCT01654484)

Timeline

2010s

  1. Jan 1, 2012

    Santen Inc. — Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2013

    Santen Inc. — Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2016

    Santen Inc. — Earliest Phase 3 Sponsor(trial)

2020s

  1. Sep 22, 2022

    Santen Inc. — Earliest FDA Approval

  2. Sep 22, 2022

    Santen Inc. — Marketing Organization

  3. Sep 22, 2022

    Santen Inc. — NDA Secondary Org

  4. Sep 22, 2022

    Santen Inc. — NDA Organization

Indications

Mechanism of action

Approval history

  • approvedSep 22, 2022

Chemistry & pharmacology

Loading structure…

SMILES

O=C(O)CNc1cccc(CN(Cc2ccc(-n3cccn3)cc2)S(=O)(=O)c2cccnc2)n1
Mol. weight
478.53 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No
Availability
Discontinued

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • de-117
  • de-117

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06666855Phase 3Nov 30, 2024Santen Inc.
NCT03858894Phase 2Jan 28, 2019Santen Inc.
NCT03697811Phase 3Sep 27, 2018Santen Inc.
NCT03691649Phase 3Sep 13, 2018Santen Inc.
NCT03691662Phase 3Sep 13, 2018Santen Inc.
NCT02981446Phase 3Nov 1, 2016Santen Inc.
NCT02822742Phase 3Jul 1, 2016Santen Inc.
NCT02822729Phase 3Jul 1, 2016Santen Inc.
NCT02650063Phase 1Dec 1, 2015Santen Inc.
NCT02623738Phase 2/Phase 3 (Phase 3)Nov 1, 2015Santen Inc.
NCT02179008Phase 2Jun 1, 2014Santen Inc.
NCT01868126Phase 2May 1, 2013Santen Inc.
NCT01654484Phase 1/Phase 2 (Phase 2)Jul 1, 2012Santen Inc.
Showing 13 of 13 trials
Page 1 / 1

Organizations

Research & Development (1)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Santen Inc.For profit131332012
1 organizations
Page 1 / 1

Marketing (3)

OrganizationOrg typeRelationshipDate
Santen Inc.For profitMKTGSep 22, 2022
Santen Inc.For profitNDA2Sep 22, 2022
Santen Inc.For profitNDASep 22, 2022