cyanoacrylate
Small moleculeexperimental
Cyanoacrylates are a family of strong fast-acting adhesives with industrial, medical, and household uses. They are derived from ethyl cyanoacrylate and related esters. The cyanoacrylate group in the monomer rapidly polymerizes in the presence of water to form long, strong chains. — Wikipedia
Clinical trial activity
14 trials · 13 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
1
Phase 3
1
Phase 4
2
Earliest trial started Nov 1, 2004 (NCT00799851)
Timeline
Indications
Approved for
Mechanism of action
- UnclearUnclear
Unclear unclear
Chemistry & pharmacology
Loading structure…
SMILES
C=C(C#N)C(=O)OC- Mol. weight
- 111.1 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- Yes
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaCyanoacrylate ↗
- ChEMBLCHEMBL2106424 ↗
Also known as
- cyanoacrylate
- cyanoacrylate
- cyanoacrylate
- mecrilate
- mecrilate
- mecrylate
- mecrylate
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07086482 | Early Phase 1 (Phase 1) | Aug 4, 2025 | Beirut Arab University |
| NCT06116539 | Phase 1 | Jan 31, 2024 | University of Alfonso X El Sabio |
| NCT05280353 | N/A | Apr 1, 2022 | Hospital de Mataró, Omphis Foundation |
| NCT05437744 | N/A | Dec 12, 2021 | Alexandria University |
| NCT04692805 | N/A | Jan 5, 2021 | Huazhong University of Science and Technology |
| NCT06106971 | Phase 3 | Jun 28, 2018 | Kaohsiung Medical University |
| NCT02468206 | N/A | Jun 1, 2015 | Sichuan University |
| NCT02468180 | N/A | Jun 1, 2015 | Sichuan University |
| NCT02468167 | N/A | Jun 1, 2015 | Sichuan University |
| NCT02504723 | Phase 4 | Jan 1, 2011 | Taichung Veterans General Hospital |
| NCT01111474 | N/A | Aug 31, 2008 | Federal University of Sao Paulo, Federal University of the Valleys of Jequitinhonha and Mucuri |
| NCT00888784 | N/A | Aug 1, 2006 | Govind Ballabh Pant Institute of Postgraduate Medical Education and Research |
| NCT00905996 | N/A | Aug 1, 2006 | Govind Ballabh Pant Institute of Postgraduate Medical Education and Research |
| NCT00799851 | Phase 4 | Nov 1, 2004 | University of Sao Paulo |
Showing 14 of 14 trials
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Organizations
Research & Development (13)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Sichuan University | Academic/Hospital | 3 | 3 | 1 | 2015 |
| Govind Ballabh Pant Institute of Postgraduate Medical Education and Research | Academic/Hospital | 2 | 2 | 1 | 2006 |
| Alexandria University | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Beirut Arab University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Federal University of Sao Paulo | Academic/Hospital | 1 | 1 | 1 | 2008 |
| Federal University of the Valleys of Jequitinhonha and Mucuri | Academic/Hospital | 1 | 0 | 1 | 2008 |
| Hospital de Mataró | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Huazhong University of Science and Technology | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Kaohsiung Medical University | Academic/Hospital | 1 | 1 | 1 | 2018 |
| Omphis Foundation | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Taichung Veterans General Hospital | Academic/Hospital | 1 | 1 | 1 | 2011 |
| University of Alfonso X El Sabio | Academic/Hospital | 1 | 1 | 1 | 2024 |
| University of Sao Paulo | Academic/Hospital | 1 | 1 | 1 | 2004 |
13 organizations
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