crs-207
Vaccineexperimental
Clinical trial activity
11 trials · 10 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
9
Phase 3
0
Phase 4
0
Earliest trial started Dec 1, 2007 (NCT00585845)
Timeline
Indications
Studied for
- Adenocarcinoma · Phase 1
- Carcinoma, Non-Small-Cell Lung · Phase 1
- Esophageal Neoplasms · Phase 2
- Fallopian Tube Neoplasms · Phase 1/Phase 2
- Hamartoma · Phase 1/Phase 2
- Mesothelioma · Phase 1
- Mesothelioma, Malignant · Phase 2
- Ovarian Neoplasms · Phase 1/Phase 2
- Pancreatic Neoplasms · Phase 2
- Stomach Neoplasms · Phase 2
Mechanism of action
- MesothelinImmunity, active
MSLN immunity, active
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- crs-207
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05014776 | Phase 2 | Dec 31, 2021 | Johns Hopkins University, Lustgarten Foundation |
| NCT03190265 | Phase 2 | Oct 1, 2017 | Aduro BioTech, Bristol-Myers Squibb, Johns Hopkins University |
| NCT03006302 | Phase 2 | Jun 1, 2017 | Johns Hopkins University |
| NCT03175172 | Phase 2 | Jun 1, 2017 | Aduro BioTech, Merck |
| NCT03122548 | Phase 2 | Jun 1, 2017 | Aduro BioTech, Merck |
| NCT02575807 | Phase 1/Phase 2 (Phase 2) | Jan 1, 2016 | Aduro BioTech, Incyte |
| NCT02243371 | Phase 2 | Dec 1, 2014 | Aduro BioTech, American Association for Cancer Research, Bristol-Myers Squibb, Johns Hopkins University, Stand Up To Cancer |
| NCT02004262 | Phase 2 | Jan 1, 2014 | Aduro BioTech |
| NCT01675765 | Phase 1 | Aug 1, 2012 | Aduro BioTech, National Cancer Institute (NCI) |
| NCT01417000 | Phase 2 | Sep 1, 2011 | Aduro BioTech, Johns Hopkins University |
| NCT00585845 | Phase 1 | Dec 1, 2007 | Anza Therapeutics, Inc. |
Showing 11 of 11 trials
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Organizations
Research & Development (10)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Aduro BioTech | For profit | 8 | 6 | 2 | 2011 |
| Johns Hopkins University | Academic/Hospital | 5 | 4 | 1 | 2011 |
| Bristol-Myers Squibb | For profit | 2 | 0 | 1 | 2014 |
| Merck | For profit | 2 | 0 | 1 | 2017 |
| American Association for Cancer Research | Academic/Hospital | 1 | 0 | 1 | 2014 |
| Anza Therapeutics, Inc. | For profit | 1 | 1 | 1 | 2007 |
| Incyte | For profit | 1 | 0 | 1 | 2016 |
| Lustgarten Foundation | Academic/Hospital | 1 | 0 | 1 | 2021 |
| National Cancer Institute (NCI) | Government | 1 | 0 | 1 | 2012 |
| Stand Up To Cancer | Academic/Hospital | 1 | 0 | 1 | 2014 |
10 organizations
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