thk-5351
Small moleculeexperimentalImaging agent
Clinical trial activity
9 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
7
Phase 3
0
Phase 4
0
Earliest trial started Dec 1, 2015 (NCT02686216)
Timeline
Indications
Mechanism of action
- Unspecified targetOTHER
Diagnostic
- Unspecified targetRadiopharmaceutical
radiopharmaceutical
Chemistry & pharmacology
Loading structure…
SMILES
CNc1ccc(-c2ccc3cc(OC[C@H](O)CF)ccc3n2)cn1- Mol. weight
- 327.36 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Imaging
- 18-fluorine
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4650352 ↗
Also known as
- 18f thk-5351
- 18f-thk-5351
- thk-5351
- thk-5351
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04318626 | Phase 2 | May 1, 2020 | Chang Gung University |
| NCT03430869 | Phase 2 | Mar 23, 2018 | Chang Gung University |
| NCT04572477 | Phase 2 | Jun 1, 2017 | Chang Gung University |
| NCT03024944 | Phase 2 | Jun 1, 2017 | Columbia University, National Institute on Aging (NIA) |
| NCT03112096 | Phase 1 | May 17, 2017 | University of Ulsan |
| NCT02884492 | Phase 2 | Jul 1, 2016 | Columbia University, National Institute on Aging (NIA) |
| NCT04588649 | Phase 2 | Jan 4, 2016 | Chang Gung University |
| NCT02656498 | Phase 2 | Jan 1, 2016 | Korea Health Industry Development Institute, Sungkyunkwan University, University of Ulsan |
| NCT02686216 | Phase 1 | Dec 1, 2015 | Chang Gung University |
Showing 9 of 9 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Chang Gung University | Academic/Hospital | 5 | 5 | 2 | 2015 |
| Columbia University | Academic/Hospital | 2 | 2 | 1 | 2016 |
| National Institute on Aging (NIA) | Government | 2 | 0 | 1 | 2016 |
| University of Ulsan | Academic/Hospital | 2 | 2 | 2 | 2016 |
| Korea Health Industry Development Institute | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Sungkyunkwan University | Academic/Hospital | 1 | 0 | 1 | 2016 |
6 organizations
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