thymidine
Small moleculeexperimental
Thymidine, also known as deoxythymidine, deoxyribosylthymine, or thymine deoxyriboside, is a pyrimidine deoxynucleoside. Deoxythymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in G1/early S phase. The prefix deoxy- is often left out since there are no precursors of thymine nucleotides involved in RNA synthesis. — Wikipedia
Clinical trial activity
4 trials · 12 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
2
Phase 3
0
Phase 4
0
Earliest trial started Mar 1, 1995 (NCT00004658)
Timeline
Indications
Studied for
- 5'-Nucleotidase · Phase 2
- Bone Marrow Failure Disorders · Phase 1
- Cerebellum · Phase 1
- Deficiency Diseases · Phase 1/Phase 2
- DNA, Mitochondrial · Phase 1/Phase 2
- Double Outlet Right Ventricle · Phase 1
- Dyskeratosis Congenita · Phase 1
- Lung Diseases, Interstitial · Phase 1
- Neutrophils · Phase 1
- Pulmonary Fibrosis · Phase 1
- Telomere · Phase 1
- Tetralogy of Fallot · Phase 1
Mechanism of action
- thymidineSupplementation
thymidine supplementation
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaThymidine ↗
Also known as
- thymidine
- thymidine
- thymidine
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06817590 | Phase 1 | Jun 30, 2025 | Harvard University |
| NCT04713657 | Phase 1 | Oct 31, 2021 | University of Pittsburgh |
| NCT03639701 | Phase 1/Phase 2 (Phase 2) | May 16, 2017 | CIBERER, Columbia University, Medical Research Council Mitochondrial Biology Unit, Muscular Dystrophy Association, Universidad Autonoma de Barcelona, Universidad Carlos III Madrid, Universidad Complutense de Madrid, University of Seville |
| NCT00004658 | Phase 2 | Mar 1, 1995 | National Center for Research Resources (NCRR), University of California, San Diego |
Showing 4 of 4 trials
Page 1 / 1
Organizations
Research & Development (12)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| CIBERER | Academic/Hospital | 1 | 0 | 1 | 2017 |
| Columbia University | Academic/Hospital | 1 | 1 | 1 | 2017 |
| Harvard University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Medical Research Council Mitochondrial Biology Unit | Academic/Hospital | 1 | 0 | 1 | 2017 |
| Muscular Dystrophy Association | Academic/Hospital | 1 | 0 | 1 | 2017 |
| National Center for Research Resources (NCRR) | Government | 1 | 1 | 1 | 1995 |
| Universidad Autonoma de Barcelona | Academic/Hospital | 1 | 0 | 1 | 2017 |
| Universidad Carlos III Madrid | Academic/Hospital | 1 | 0 | 1 | 2017 |
| Universidad Complutense de Madrid | Academic/Hospital | 1 | 0 | 1 | 2017 |
| University of California, San Diego | Academic/Hospital | 1 | 0 | 1 | 1995 |
| University of Pittsburgh | Academic/Hospital | 1 | 1 | 1 | 2021 |
| University of Seville | Academic/Hospital | 1 | 0 | 1 | 2017 |
12 organizations
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