mk-5684

Small moleculeexperimental

Clinical trial activity

11 trials · 3 clinical orgs · 0 marketing orgs

Phase 1
9
Phase 2
4
Phase 3
2
Phase 4
0

Earliest trial started Nov 14, 2023 (NCT06104449)

Timeline

2020s

  1. Jan 1, 2023

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2023

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CS(=O)(=O)N1CCC(COc2coc(CN3Cc4ccccc4C3)cc2=O)CC1
Mol. weight
418.52 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06863272Phase 1/Phase 2 (Phase 2)Jun 17, 2025Daiichi Sankyo, Merck
NCT06860243Phase 1Apr 11, 2025Merck
NCT06814132Phase 1Mar 14, 2025Merck
NCT06633419Phase 1Jan 2, 2025Merck
NCT06566989Phase 1Sep 19, 2024Merck, Orion Corporation
NCT06554639Phase 1Jul 11, 2024Merck
NCT06353386Phase 1/Phase 2 (Phase 2)May 20, 2024Merck, Orion Corporation
NCT06136598Phase 1Dec 25, 2023Merck
NCT06136624Phase 3Dec 22, 2023Merck, Orion Corporation
NCT06136650Phase 3Dec 18, 2023Merck, Orion Corporation
NCT06104449Phase 1Nov 14, 2023Merck
Showing 11 of 11 trials
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Organizations

Research & Development (3)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
MerckFor profit111132023
Orion CorporationFor profit4032023
Daiichi SankyoFor profit1012025
3 organizations
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