recombinant oncolytic herpes simplex virus type 1 (r130)
Biologicalexperimental
Clinical trial activity
8 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
8
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Dec 2, 2022 (NCT05801783)
Timeline
2020s
- Jan 1, 2022
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
- Brain Neoplasms · Early Phase 1
- Breast Neoplasms · Early Phase 1
- Bronchial Neoplasms · Early Phase 1
- Carcinoma · Early Phase 1
- Carcinoma, Non-Small-Cell Lung · Early Phase 1
- Colorectal Neoplasms · Early Phase 1
- Digestive System Neoplasms · Early Phase 1
- Ear Neoplasms · Early Phase 1
- Endometrial Neoplasms · Early Phase 1
- Esophageal Neoplasms · Early Phase 1
- Fallopian Tube Neoplasms · Early Phase 1
- Genital Neoplasms, Female · Early Phase 1
- Head and Neck Neoplasms · Early Phase 1
- Kidney Neoplasms · Early Phase 1
- Laryngeal Neoplasms · Early Phase 1
- Liver Neoplasms · Early Phase 1
- Lung Neoplasms · Early Phase 1
- Melanoma · Early Phase 1
- Neoplasms · Early Phase 1
- Nose Neoplasms · Early Phase 1
- Osteosarcoma · Early Phase 1
- Otorhinolaryngologic Neoplasms · Early Phase 1
- Ovarian Neoplasms · Early Phase 1
- Pancreatic Neoplasms · Early Phase 1
- Peritoneal Neoplasms · Early Phase 1
- Pharyngeal Neoplasms · Early Phase 1
- Sarcoma · Early Phase 1
- Small Cell Lung Carcinoma · Early Phase 1
- Stomach Neoplasms · Early Phase 1
- Uterine Cervical Neoplasms · Early Phase 1
Mechanism of action
- Oncolytic virusOTHER
Oncolytic virus other
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06171282 | Early Phase 1 (Phase 1) | Jul 12, 2023 | Jiao Tong University, Shanghai Yunying Medical Technology |
| NCT05961111 | Early Phase 1 (Phase 1) | Jun 24, 2023 | Shanghai Yunying Medical Technology, Yishui Central Hospital of LINYI |
| NCT05851456 | Early Phase 1 (Phase 1) | Apr 10, 2023 | Jiao Tong University, Shanghai Yunying Medical Technology |
| NCT05886075 | Early Phase 1 (Phase 1) | Mar 30, 2023 | Shanghai Yunying Medical Technology |
| NCT05830240 | Early Phase 1 (Phase 1) | Mar 27, 2023 | Fudan University, Shanghai Yunying Medical Technology |
| NCT05860374 | Early Phase 1 (Phase 1) | Mar 2, 2023 | Shanghai Yunying Medical Technology, Xuzhou Medical University |
| NCT05812677 | Early Phase 1 (Phase 1) | Feb 6, 2023 | Huazhong University of Science and Technology, Shanghai Yunying Medical Technology |
| NCT05801783 | Early Phase 1 (Phase 1) | Dec 2, 2022 | Huazhong University of Science and Technology, Shanghai Yunying Medical Technology |
Showing 8 of 8 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Shanghai Yunying Medical Technology | For profit | 8 | 8 | 1 | 2022 |
| Huazhong University of Science and Technology | Academic/Hospital | 2 | 0 | 1 | 2022 |
| Jiao Tong University | Academic/Hospital | 2 | 0 | 1 | 2023 |
| Fudan University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Xuzhou Medical University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Yishui Central Hospital of LINYI | Academic/Hospital | 1 | 0 | 1 | 2023 |
6 organizations
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