[f-18]fapi-74
Small moleculeexperimentalImaging agent
Clinical trial activity
14 trials · 14 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
6
Phase 3
4
Phase 4
0
Earliest trial started Apr 1, 2021 (NCT05884463)
Timeline
Indications
Studied for
- Carcinoma, Hepatocellular · Phase 2
- Cholangiocarcinoma · Phase 2/Phase 3
- Colorectal Neoplasms · Phase 2
- Dermatitis · Phase 2
- Esophageal Neoplasms · Phase 3
- Esophagogastric Junction · Phase 3
- Fibrosis · Phase 1
- Gastrointestinal Neoplasms · Phase 2
- Mesothelioma · Phase 2
- Neoplasms · Phase 1
- Ovarian Neoplasms · Phase 2
- Pancreatic Neoplasms · Phase 3
- Pheochromocytoma · Phase 2
- Positron Emission Tomography Computed Tomography · Phase 2/Phase 3
- Sarcoma · Phase 2
- Small Cell Lung Carcinoma · Phase 2
- Stomach Neoplasms · Phase 3
- Urinary Bladder Neoplasms · Phase 2
Mechanism of action
- Unspecified targetRadiopharmaceutical
radiopharmaceutical
Chemistry & pharmacology
- Imaging
- 18-Fluoride
Oral
No
Parenteral
No
Topical
No
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07285993 | Phase 2 | Dec 30, 2025 | Icahn School of Medicine at Mount Sinai |
| NCT07217717 | Phase 3 | Dec 23, 2025 | Sofie |
| NCT07217704 | Phase 3 | Nov 14, 2025 | Sofie |
| NCT07018661 | Phase 2/Phase 3 (Phase 3) | Jul 3, 2025 | Leiden University |
| NCT06503146 | Phase 2 | Nov 17, 2024 | National Cancer Institute (NCI) |
| NCT06568783 | Phase 2 | Oct 31, 2024 | Stanford University |
| NCT06355427 | Phase 2/Phase 3 (Phase 3) | Sep 1, 2024 | Erasmus University Rotterdam, University of Amsterdam, Utrecht University |
| NCT06413355 | Phase 1 | Jul 16, 2024 | University of Pennsylvania |
| NCT05641896 | Phase 2 | Feb 28, 2023 | Sofie |
| NCT05749302 | Phase 1 | Jan 8, 2023 | Chinese Academy of Medical Sciences |
| NCT05691894 | Early Phase 1 (Phase 1) | Nov 2, 2022 | Jiangnan University |
| NCT05810324 | N/A | Jul 1, 2022 | Jilin University |
| NCT05442151 | N/A | May 9, 2022 | Osaka University |
| NCT05884463 | N/A | Apr 1, 2021 | Zhejiang University |
Showing 14 of 14 trials
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Organizations
Research & Development (14)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Sofie | For profit | 3 | 3 | 2 | 2023 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Erasmus University Rotterdam | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Icahn School of Medicine at Mount Sinai | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Jiangnan University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Jilin University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Leiden University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| National Cancer Institute (NCI) | Government | 1 | 1 | 1 | 2024 |
| Osaka University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Stanford University | Academic/Hospital | 1 | 1 | 1 | 2024 |
| University of Amsterdam | Academic/Hospital | 1 | 0 | 1 | 2024 |
| University of Pennsylvania | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Utrecht University | Academic/Hospital | 1 | 0 | 1 | 2024 |
| Zhejiang University | Academic/Hospital | 1 | 1 | 1 | 2021 |
14 organizations
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