cft7455
Small moleculeexperimental
Clinical trial activity
3 trials · 3 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
2
Phase 3
0
Phase 4
0
Earliest trial started Apr 27, 2021 (NCT04756726)
Timeline
Indications
Mechanism of action
- Protein cereblonACTIVATOR
CRBN activator
Chemistry & pharmacology
Loading structure…
SMILES
O=C1CC[C@H](N2C(=O)c3cccc4c(Cc5ccc(CN6CCOCC6)cc5)ccc2c34)C(=O)N1- Mol. weight
- 469.54 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL5095227 ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07280013 | Phase 1 | Apr 30, 2026 | C4 Therapeutics, Inc. |
| NCT07284758 | Phase 2 | Jan 31, 2026 | C4 Therapeutics, Inc., Medical College of Wisconsin, Royal Marsden Hospital NHS Trust |
| NCT04756726 | Phase 1/Phase 2 (Phase 2) | Apr 27, 2021 | C4 Therapeutics, Inc. |
Showing 3 of 3 trials
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Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| C4 Therapeutics, Inc. | For profit | 3 | 3 | 2 | 2021 |
| Medical College of Wisconsin | Academic/Hospital | 1 | 0 | 1 | 2026 |
| Royal Marsden Hospital NHS Trust | Academic/Hospital | 1 | 0 | 1 | 2026 |
3 organizations
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