cd70 car-t cells
Cell therapyexperimental
Clinical trial activity
15 trials · 15 clinical orgs · 0 marketing orgs
Phase 1
15
Phase 2
3
Phase 3
0
Phase 4
0
Earliest trial started Jun 16, 2016 (NCT02830724)
Timeline
2010s
- Jan 1, 2016
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
- Breast Neoplasms · Phase 1/Phase 2
- Carcinoma, Renal Cell · Phase 1/Phase 2
- Genital Neoplasms, Female · Phase 1
- Hematologic Neoplasms · Phase 1
- Leukemia, Myeloid, Acute · Phase 1
- Lymphoma · Phase 1/Phase 2
- Lymphoma, Non-Hodgkin · Early Phase 1
- Melanoma · Phase 1/Phase 2
- Multiple Myeloma · Early Phase 1
- Myelodysplastic Syndromes · Phase 1
- Neoplasm Metastasis · Phase 1
- Neoplasms · Phase 1/Phase 2
- Ovarian Neoplasms · Phase 1/Phase 2
- Pancreatic Neoplasms · Phase 1/Phase 2
- Precursor Cell Lymphoblastic Leukemia-Lymphoma · Phase 1
- Urogenital Neoplasms · Phase 1
- Uterine Cervical Neoplasms · Phase 1
Mechanism of action
- CD70 antigenImmunity, passive
CD70 immunity, passive
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- anti-hcd70 car pbl
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06326463 | Phase 1 | Dec 31, 2024 | St. Jude Children's Hospital |
| NCT06586658 | Early Phase 1 (Phase 1) | Sep 6, 2024 | Government of China, Second Military Medical University |
| NCT06394622 | Phase 1 | Apr 11, 2024 | Fudan University |
| NCT06215950 | Phase 1 | Jan 10, 2024 | Chongqing Precision Biotech Co., Ltd, Wannan Medical College |
| NCT06010875 | Phase 1 | Nov 30, 2023 | Chongqing Precision Biotech Co., Ltd, Nanchang University |
| NCT05990621 | Phase 1 | Jul 31, 2023 | Changhai Hospital, UTC Therapeutics Inc. |
| NCT06182735 | Phase 1 | Jul 17, 2023 | Fudan University |
| NCT05948033 | Phase 1/Phase 2 (Phase 2) | Jul 15, 2023 | People's Liberation Army of China, UTC Therapeutics Inc. |
| NCT05947487 | Phase 1/Phase 2 (Phase 2) | Jul 15, 2023 | People's Liberation Army of China, UTC Therapeutics Inc. |
| NCT05468190 | Phase 1 | Jul 17, 2022 | Chongqing Precision Biotech Co., Ltd, Henan Medical University |
| NCT05518253 | Phase 1 | May 30, 2022 | Chongqing Precision Biotech Co., Ltd, Zhejiang University |
| NCT05420519 | Phase 1 | Dec 31, 2021 | Chongqing Precision Biotech Co., Ltd, Shandong University |
| NCT05420545 | Phase 1 | Dec 31, 2021 | Chongqing Precision Biotech Co., Ltd, Shandong University |
| NCT04662294 | Early Phase 1 (Phase 1) | Nov 18, 2021 | Yake Biotechnology Ltd., Zhejiang University |
| NCT02830724 | Phase 1/Phase 2 (Phase 2) | Jun 16, 2016 | National Cancer Institute (NCI) |
Showing 15 of 15 trials
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Organizations
Research & Development (15)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Chongqing Precision Biotech Co., Ltd | For profit | 6 | 5 | 1 | 2021 |
| UTC Therapeutics Inc. | For profit | 3 | 0 | 2 | 2023 |
| Fudan University | Academic/Hospital | 2 | 2 | 1 | 2023 |
| People's Liberation Army of China | Government | 2 | 2 | 1 | 2023 |
| Shandong University | Academic/Hospital | 2 | 0 | 1 | 2021 |
| Zhejiang University | Academic/Hospital | 2 | 2 | 1 | 2021 |
| Changhai Hospital | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Government of China | Government | 1 | 0 | 1 | 2024 |
| Henan Medical University | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Nanchang University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| National Cancer Institute (NCI) | Government | 1 | 1 | 1 | 2016 |
| Second Military Medical University | Government | 1 | 1 | 1 | 2024 |
| St. Jude Children's Hospital | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Wannan Medical College | Academic/Hospital | 1 | 0 | 1 | 2024 |
| Yake Biotechnology Ltd. | Government | 1 | 0 | 1 | 2021 |
15 organizations
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